Klin Monbl Augenheilkd 2022; 239(12): 1433-1439
DOI: 10.1055/a-1937-9901
Übersicht

Selective Stimulation of the Different Photoreceptor Classes by Silent Substitution in Psychophysical and Electroretinographic Measurements

Article in several languages: deutsch | English
Augenklinik mit Poliklinik, Universitätsklinikum Erlangen, Deutschland
,
Jan Kremers
Augenklinik mit Poliklinik, Universitätsklinikum Erlangen, Deutschland
› Author Affiliations
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Abstract

The silent substitution technique allows creating photoreceptor-selective stimuli for psychophysical and electrophysiological tests. In contrast to other techniques, the purpose of silent substitution is not to make the targeted photoreceptor type more sensitive in comparison to the other types, but to make the stimulus invisible (“silent”) to the other photoreceptor types. This allows selectivity independent of the retinal state of adaptation and enables comparing photoreceptor types under identical conditions. The foundations of these techniques will be explained in this paper. Furthermore, the importance of postreceptoral processing for the perception of photoreceptor-selective stimuli is discussed here. Although this technique is currently only available in specialized vision science labs, there is an enormous potential for clinical application.



Publication History

Received: 31 May 2022

Accepted: 02 September 2022

Article published online:
09 December 2022

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