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Klin Monbl Augenheilkd 2022; 239(12): 1447-1453
DOI: 10.1055/a-1947-5562
Übersicht

Retinal and Choroidal Ultra-Widefield OCT – Technology, Insights, and Clinical Relevance

Article in several languages: deutsch | English
Claudia Brockmann
Klinik und Poliklinik für Augenheilkunde, Universitätsmedizin Rostock, Deutschland
,
Tobias Brockmann
Klinik und Poliklinik für Augenheilkunde, Universitätsmedizin Rostock, Deutschland
,
Adrianna Urszula Dera
Klinik und Poliklinik für Augenheilkunde, Universitätsmedizin Rostock, Deutschland
,
Ha-Vy Do
Klinik und Poliklinik für Augenheilkunde, Universitätsmedizin Rostock, Deutschland
,
Wladislaw Rusch
Klinik und Poliklinik für Augenheilkunde, Universitätsmedizin Rostock, Deutschland
,
Friederike Schaub
Klinik und Poliklinik für Augenheilkunde, Universitätsmedizin Rostock, Deutschland
,
Thomas Armin Fuchsluger
Klinik und Poliklinik für Augenheilkunde, Universitätsmedizin Rostock, Deutschland
,
Oliver Stachs
Klinik und Poliklinik für Augenheilkunde, Universitätsmedizin Rostock, Deutschland
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Abstract

As one of the most state-of-the-art procedures for retinal and choroidal imaging, ultra-widefield optical coherence tomography (UWF-OCT) offers significant gains in terms of information pertaining to peripheral retinal lesions and their differential diagnoses. In particular, it enables the presence of minimal accumulations of subretinal fluid to be assessed in detail and then documented. It also enables choroidal expansion of choroidal lesions to be precisely measured. Similar to conventional OCT, its only limitations relate to patient compliance and opacities of the ocular media. While the pupil width is somewhat less important here, the quality of the images is nevertheless better with the patient under medication-induced mydriasis. Used in combination with UWF fundus photography, UWF-OCT is a helpful tool for assessing and monitoring peripheral retinal and choroidal lesions.

Key words

ultra-widefield - optical coherence tomography - choroidal lesion - retinoschisis


Publication History

Received: 01 August 2022

Accepted: 14 September 2022

Article published online:
09 December 2022

© 2022. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

  • Literatur

  • 1 Hee MR, Baumal CR, Puliafito CA. et al. Optical coherence tomography of age-related macular degeneration and choroidal neovascularization. Ophthalmology 1996; 103: 1260-1270
    CrossrefPubMedSearch in Google Scholar
  • 2 Coscas F, Coscas G, Souied E. et al. Optical coherence tomography identification of occult choroidal neovascularization in age-related macular degeneration. Am J Ophthalmol 2007; 144: 592-599
    CrossrefPubMedSearch in Google Scholar
  • 3 Pieroni CG, Witkin AJ, Ko TH. et al. Ultrahigh resolution optical coherence tomography in non-exudative age related macular degeneration. Br J Ophthalmol 2006; 90: 191-197
    CrossrefPubMedSearch in Google Scholar
  • 4 Rosenfeld PJ, Moshfeghi AA, Puliafito CA. Optical coherence tomography findings after an intravitreal injection of bevacizumab (avastin) for neovascular age-related macular degeneration. Ophthalmic Surg Lasers Imaging 2005; 36: 331-335
    CrossrefPubMedSearch in Google Scholar
  • 5 Sayanagi K, Sharma S, Yamamoto T. et al. Comparison of spectral-domain versus time-domain optical coherence tomography in management of age-related macular degeneration with ranibizumab. Ophthalmology 2009; 116: 947-955
    CrossrefPubMedSearch in Google Scholar
  • 6 Framme C, Panagakis G, Birngruber R. Effects on choroidal neovascularization after anti-VEGF Upload using intravitreal ranibizumab, as determined by spectral domain-optical coherence tomography. Invest Ophthalmol Vis Sci 2010; 51: 1671-1676
    CrossrefPubMedSearch in Google Scholar
  • 7 Hee MR, Puliafito CA, Duker JS. et al. Topography of diabetic macular edema with optical coherence tomography. Ophthalmology 1998; 105: 360-370
    CrossrefPubMedSearch in Google Scholar
  • 8 Rosenfeld PJ, Fung AE, Puliafito CA. Optical coherence tomography findings after an intravitreal injection of bevacizumab (avastin) for macular edema from central retinal vein occlusion. Ophthalmic Surg Lasers Imaging 2005; 36: 336-339
    CrossrefPubMedSearch in Google Scholar
  • 9 Rehak J, Rehak M. Branch retinal vein occlusion: pathogenesis, visual prognosis, and treatment modalities. Curr Eye Res 2008; 33: 111-131
    CrossrefPubMedSearch in Google Scholar
  • 10 Karim R, Sykakis E, Lightman S. et al. Interventions for the treatment of uveitic macular edema: a systematic review and meta-analysis. Clin Ophthalmol 2013; 7: 1109-1144
    CrossrefPubMedSearch in Google Scholar
  • 11 Sudhalkar A, Chhablani J, Vasavada A. et al. Intravitreal dexamethasone implant for recurrent cystoid macular edema due to Irvine-Gass syndrome: a prospective case series. Eye (Lond) 2016; 30: 1549-1557
    CrossrefPubMedSearch in Google Scholar
  • 12 Minami Y, Ishiko S, Takai Y. et al. Retinal changes in juvenile X linked retinoschisis using three dimensional optical coherence tomography. Br J Ophthalmol 2005; 89: 1663-1664
    CrossrefPubMedSearch in Google Scholar
  • 13 Duncker T, Greenberg JP, Ramachandran R. et al. Quantitative fundus autofluorescence and optical coherence tomography in best vitelliform macular dystrophy. Invest Ophthalmol Vis Sci 2014; 55: 1471-1482
    CrossrefPubMedSearch in Google Scholar
  • 14 Tanner V, Chauhan DS, Jackson TL. et al. Optical coherence tomography of the vitreoretinal interface in macular hole formation. Br J Ophthalmol 2001; 85: 1092-1097
    CrossrefPubMedSearch in Google Scholar
  • 15 Ko TH, Fujimoto JG, Duker JS. et al. Comparison of ultrahigh- and standard-resolution optical coherence tomography for imaging macular hole pathology and repair. Ophthalmology 2004; 111: 2033-2043
    CrossrefPubMedSearch in Google Scholar
  • 16 Brockmann T, Steger C, Weger M. et al. Risk assessment of idiopathic macular holes undergoing vitrectomy with dye-assisted internal limiting membrane peeling. Retina 2013; 33: 1132-1136
    CrossrefPubMedSearch in Google Scholar
  • 17 Ehlers JP, Tam T, Kaiser PK. et al. Utility of intraoperative optical coherence tomography during vitrectomy surgery for vitreomacular traction syndrome. Retina 2014; 34: 1341-1346
    CrossrefPubMedSearch in Google Scholar
  • 18 Wessing A. Fluorescein Angiography of the Retina. Textbook and Atlas. Translated by G.K. von Noorden. St. Louis: Mosby; 1969
    Search in Google Scholar
  • 19 Kozak I, Morrison VL, Clark TM. et al. Discrepancy between fluorescein angiography and optical coherence tomography in detection of macular disease. Retina 2008; 28: 538-544
    CrossrefPubMedSearch in Google Scholar
  • 20 Kogure K, David NJ, Yamanouchi U. et al. Infrared absorption angiography of the fundus circulation. Arch Ophthalmol 1970; 83: 209-214
    CrossrefPubMedSearch in Google Scholar
  • 21 Hochheimer BF. Angiography of the retina with indocyanine green. Arch Ophthalmol 1971; 86: 564-565
    CrossrefPubMedSearch in Google Scholar
  • 22 Talks J, Koshy Z, Chatzinikolas K. Use of optical coherence tomography, fluorescein angiography and indocyanine green angiography in a screening clinic for wet age-related macular degeneration. Br J Ophthalmol 2007; 91: 600-601
    CrossrefPubMedSearch in Google Scholar
  • 23 Huang Y, Zhang Q, Thorell MR. et al. Swept-source OCT angiography of the retinal vasculature using intensity differentiation-based optical microangiography algorithms. Ophthalmic Surg Lasers Imaging Retina 2014; 45: 382-389
    CrossrefPubMedSearch in Google Scholar
  • 24 Spaide RF, Fujimoto JG, Waheed NK. Optical Coherence Tomography Angiography. Retina 2015; 35: 2161-2162
    CrossrefPubMedSearch in Google Scholar
  • 25 Spaide RF, Klancnik JM, Cooney MJ. Retinal vascular layers imaged by fluorescein angiography and optical coherence tomography angiography. JAMA Ophthalmol 2015; 133: 45-50
    Search in Google Scholar
  • 26 Spaide RF. Optical Coherence Tomography Angiography Signs of Vascular Abnormalization With Antiangiogenic Therapy for Choroidal Neovascularization. Am J Ophthalmol 2015; 160: 6-16
    CrossrefPubMedSearch in Google Scholar
  • 27 Witmer MT, Kiss S. Wide-field imaging of the retina. Surv Ophthalmol 2013; 58: 143-154
    CrossrefPubMedSearch in Google Scholar
  • 28 Witmer MT, Parlitsis G, Patel S. et al. Comparison of ultra-widefield fluorescein angiography with the Heidelberg Spectralis(®) noncontact ultra-widefield module versus the Optos(®) Optomap(®). Clin Ophthalmol 2013; 7: 389-394
    CrossrefPubMedSearch in Google Scholar
  • 29 Abalem MF, Otte B, Andrews C. et al. Peripheral Visual Fields in ABCA4 Stargardt Disease and Correlation With Disease Extent on Ultra-widefield Fundus Autofluorescence. Am J Ophthalmol 2017; 184: 181-188
    CrossrefPubMedSearch in Google Scholar
  • 30 Choudhry N, Golding J, Manry MW. et al. Ultra-Widefield Steering-Based Spectral-Domain Optical Coherence Tomography Imaging of the Retinal Periphery. Ophthalmology 2016; 123: 1368-1374
    CrossrefPubMedSearch in Google Scholar
  • 31 Holmes J. OCT technology development: where are we now? A commercial perspective. J Biophotonics 2009; 2: 347-352
    CrossrefPubMedSearch in Google Scholar
  • 32 Fercher A, Hitzenberger C, Kamp G. et al. Measurement of intraocular distances by backscattering spectral interferometry. Opt Comm 1995; 117: 43-48
    CrossrefPubMedSearch in Google Scholar
  • 33 Fercher AF, Drexler W, Hitzenberger CK. et al. Optical coherence tomography-principles and applications. Rep Prog Physics 2003; 66: 239-303
    CrossrefPubMedSearch in Google Scholar
  • 34 Huang D, Swanson EA, Lin CP. et al. Optical coherence tomography. Science 1991; 254: 1178-1181
    CrossrefPubMedSearch in Google Scholar
  • 35 Forooghian F, Cukras C, Meyerle CB. et al. Evaluation of time domain and spectral domain optical coherence tomography in the measurement of diabetic macular edema. Invest Ophthalmol Vis Sci 2008; 49: 4290-4296
    CrossrefPubMedSearch in Google Scholar
  • 36 Ung C, Laíns I, Silverman RF. et al. Evaluation of choroidal lesions with swept-source optical coherence tomography. Br J Ophthalmol 2019; 103: 88-93
    CrossrefPubMedSearch in Google Scholar