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DOI: 10.1055/a-1949-7549
Case report: Acute transverse myelitis in COVID-19 infection with delayed onset of pulmonary manifestation
Fallbericht: Akute Myelitis transversa in COVID-19-Infektion mit verzögertem Beginn der pulmonalen Manifestation The author received no financial support for the research, authorship, and/or publication of this article.Introduction
COVID-19 disease, caused by the novel beta-coronavirus SARS-CoV-2, has become a global pandemic, with more than 220 million confirmed cases reported to the World Health Organization (WHO) by September 2021 (WHO Coronavirus (COVID-19) Dashboard. https://covid19.who.int. Accessed 6 September 2021). The virus causes mild to moderate respiratory illness and most patients recover without requiring special treatment. However, some will become seriously ill with atypical pneumonia and acute respiratory distress syndrome (ARDS), with some cases being fatal. SARS-CoV-2 enters human cells by binding to angiotensin-converting enzyme-2 (ACE2) receptors. These receptors are expressed not only in the lung epithelium, but also in numerous other organs and tissues, such as vascular endothelial cells, heart, brain, kidney, liver, and intestine, which explains the broad spectrum of extrapulmonary symptoms reported for COVID-19-disease (Machhi J. J Neuroimmune Pharmacol. 2020; 15(3): 359–386)
Publication History
Article published online:
17 October 2022
© 2022. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
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