Synthesis, Inhaltsverzeichnis Synthesis 2023; 55(05): 779-785DOI: 10.1055/a-1953-4534 paper Disilathiane as a Sulfur Source for the Construction of Isothiochromenes and Benzo[b]thiophenes by Copper-Catalyzed endo-Selective Hydrothiolation Autor*innen Takumi Nakajima Ryuki Takeuchi Keita Oomori Kento Ishida Yohei Ogiwara Norio Sakai ∗ Artikel empfehlen Abstract Artikel einzeln kaufen(opens in new window) Alle Artikel dieser Rubrik(opens in new window) Abstract A copper-catalyzed construction of isothiochromenes and benzo[b]thiophenes via annulation with 1,1,1,3,3,3-hexamethyldisilathiane as a sulfur source is described. In the isothiochromene synthesis, the use of the disilathiane as a sulfur source successfully controls the regioselectivity of cyclization to afford the isothiochromene as the sole product. The present strategy can be applied to the synthesis of 2-aryl/2-alkylbenzo[b]thiophenes. 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