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Synlett 2023; 34(03): 211-220
DOI: 10.1055/a-1970-4290
DOI: 10.1055/a-1970-4290
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Recent Progress towards the Transition-Metal-Catalyzed Dearomatizing Spirocyclization Reactions of Indolyl Ynones
We are grateful for the financial support from the NNSFC (22001059), the Top-Notch Talents Program of Henan Agricultural University (30500739).
Abstract
Dearomatizing spirocyclization reactions are very appealing synthetic strategies to generate functionalized three-dimensional scaffolds from simple two-dimensional precursors. Recently, the field of transition-metal-catalyzed dearomatizing spirocyclization reactions of indolyl ynones has burgeoned, as the construction of synthetically challenging quaternary spirocyclic carbons is easily achieved. In this review, we introduce an overview of advances in the transition-metal-catalyzed dearomatizing spirocyclization reactions of indolyl ynones, with the reactions being categorized according to type of catalyst.
Key words
transition-metal catalysis - indolyl ynones - dearomatization - spirocyclization - spirocyclic indoleninesPublication History
Received: 17 October 2022
Accepted after revision: 30 October 2022
Accepted Manuscript online:
30 October 2022
Article published online:
06 December 2022
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