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Synlett 2023; 34(03): 211-220
DOI: 10.1055/a-1970-4290
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Recent Progress towards the Transition-Metal-Catalyzed Dearomatizing Spirocyclization Reactions of Indolyl Ynones

Kua-Fei Wei
a   College of Sciences and College of Forestry, Henan Agricultural University, Zhengzhou 450002, P. R. of China
,
Xiao-Lei Jiang
a   College of Sciences and College of Forestry, Henan Agricultural University, Zhengzhou 450002, P. R. of China
b   Sanmenxia Polytechnic, Sanmenxia, Henan 472000, P. R. of China
,
Guang-Xin Ru
a   College of Sciences and College of Forestry, Henan Agricultural University, Zhengzhou 450002, P. R. of China
,
Xiu-Hong Zhu
a   College of Sciences and College of Forestry, Henan Agricultural University, Zhengzhou 450002, P. R. of China
,
Wen-Bo Shen∗
a   College of Sciences and College of Forestry, Henan Agricultural University, Zhengzhou 450002, P. R. of China
› InstitutsangabenWe are grateful for the financial support from the NNSFC (22001059), the Top-Notch Talents Program of Henan Agricultural University (30500739).
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Abstract

Dearomatizing spirocyclization reactions are very appealing synthetic strategies to generate functionalized three-dimensional scaffolds from simple two-dimensional precursors. Recently, the field of transition-metal-catalyzed dearomatizing spirocyclization reactions of indolyl ynones has burgeoned, as the construction of synthetically challenging quaternary spirocyclic carbons is easily achieved. In this review, we introduce an overview of advances in the transition-metal-catalyzed dearomatizing spirocyclization reactions of indolyl ynones, with the reactions being categorized according to type of catalyst.

Key words

transition-metal catalysis - indolyl ynones - dearomatization - spirocyclization - spirocyclic indolenines


Publikationsverlauf

Eingereicht: 17. Oktober 2022

Angenommen nach Revision: 30. Oktober 2022

Accepted Manuscript online:
30. Oktober 2022

Artikel online veröffentlicht:
06. Dezember 2022

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