Klin Monbl Augenheilkd 2024; 241(01): 88-94
DOI: 10.1055/a-1972-3275
Kasuistik

A Modification of the Inverted Internal Limiting Membrane Flap Technique without Heavy Liquids and Prone Posturing

Article in several languages: deutsch | English
1   Klinik für Augenheilkunde, Goethe-Universität Frankfurt, Frankfurt am Main, Deutschland
,
Sophie-Christin Ernst
2   Augenklinik, Stadtspital Zürich, Schweiz
3   Spross Research Institute, Zürich, Schweiz
,
2   Augenklinik, Stadtspital Zürich, Schweiz
3   Spross Research Institute, Zürich, Schweiz
4   Klinik für Augenheilkunde, Semmelweis Universität, Budapest, Ungarn
,
Matthias Dieter Becker
2   Augenklinik, Stadtspital Zürich, Schweiz
3   Spross Research Institute, Zürich, Schweiz
5   Ruprecht-Karls-Universität Heidelberg, Deutschland
,
2   Augenklinik, Stadtspital Zürich, Schweiz
3   Spross Research Institute, Zürich, Schweiz
6   Augenklinik, Universitätsspital Zürich, Universität Zürich, Schweiz
› Author Affiliations

Abstract

Primary closure of large macular holes remains challenging, and variations of inverted inner limiting membrane (ILM) flap surgery have been described. In the present retrospective, interventional, single-centre case series, we propose a superior flap design with minimal posturing. Eight eyes of eight patients (four women and four men) in the period between July 2020 and March 2022 underwent 23 G three-port vitrectomy with a superior inverted ILM flap and 20% SF6 endotamponade for a full thickness macular hole (MH) by the same experienced surgeon (F. M. H.). Seven MHs were classified as large (> 400 µm) and one as medium (250 – 400 µm). The mean MLD was 638.0 ± 166.4 µm (range: 353 – 851 µm). MH closure was achieved in all (8/8, 100%) patients with a single surgery. The median best-corrected visual acuity (BCVA) improved from 6/120 (Snellen) (range: finger counting [FC] to 6/19) preoperatively to 6/19 (range: FC to 6/9.5) after surgery, without any intra- or postoperative complications. The superior inverted ILM flap technique seems to be a safe and successful approach for the primary closure of large MHs. Further studies should investigate our proposed surgical technique on a larger population, potentially without air or gas endotamponade.



Publication History

Received: 30 June 2022

Accepted: 19 October 2022

Article published online:
23 December 2022

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  • References/Literatur

  • 1 Steel DH, Donachie PHJ, Aylward GW. et al. Factors affecting anatomical and visual outcome after macular hole surgery: findings from a large prospective UK cohort. Eye (Lond) 2021; 35: 316-325
  • 2 Michalewska Z, Michalewski J, Adelman RA. et al. Inverted internal limiting membrane flap technique for large macular holes. Ophthalmology 2010; 117: 2018-2025
  • 3 Hess JA, Michels S, Becker MD. [Functional and Anatomic Outcomes of Primary and Secondary Internal Limiting Membrane Transplantation in Large and Persistent Macular Holes]. Klin Monbl Augenheilkd 2018; 235: 1159-1164
  • 4 Duker JS, Kaiser PK, Binder S. et al. The International Vitreomacular Traction Study Group Classification of Vitreomacular Adhesion, Traction, and Macular Hole. Ophthalmology 2013; 120: 2611-2619
  • 5 Michalewska Z, Michalewski J, Dulczewska-Cichecka K. et al. Temporal inverted Internal Limiting Membrane Flap Technique versus Classic Inverted Internal Limiting Membrane Flap Technique: A Comparative Study. Retina 2015; 35: 1844-1850
  • 6 Ruparelia S, Tuli R, Park JSY. et al. Inverted Internal Limiting Membrane Flap Technique without Postoperative Face-Down Positioning for Macular Hole Repair. Retina 2022; 42: 548-552
  • 7 Kannan NB, Kohli P, Parida H. et al. Comparative study of inverted internal limiting membrane (ILM) flap and ILM peeling technique in large macular holes: a randomized-control trial. BMC Ophthalmol 2018; 18: 177
  • 8 Choi SR, Kang JW, Jeon JH. et al. The Efficacy of Superior Inverted Internal Limiting Membrane Flap Technique for the Treatment of Full-Thickness Macular Hole. Retina 2018; 38: 192-197
  • 9 Stopa M, Ciesielski M, Rakowicz P. Macular Hole Closure Without Endotamponade Application. Retina 2020;
  • 10 Singh DV, Reddy RR, Sharma YR. et al. Epiretinal Membrane from Uncontrolled Gliosis After Inverted ILM Flap Technique for Idiopathic Macular Hole. Ophthalmic Surg Lasers Imaging Retina 2021; 52: 663-665
  • 11 Faria MY, Ferreira NP, Cristóvao DM. et al. Tomographic Structural Changes of Retinal Layers after Internal Limiting Membrane Peeling for Macular Hole Surgery. Ophthalmic Res 2018; 59: 24-29