Großer zystischer Abdominaltumor bedingt durch eine niedrig maligne Neoplasie der Appendix

Tumoröse Veränderungen im Beckenbereich haben vielfältige Ursachen. Eine Einschätzung ist oft schwierig, und Fälle mit Fehlzuordnungen, die erst durch eine histopathologische Aufarbeitung geklärt werden konnten, sind in der Literatur beschrieben [1] [2] [3]. Bei tumorösen Veränderungen der Adnexe ist primär an einen Tumor der Adnexe bzw. Metastasen anderer abdomineller Organe – Uterus, Harnblase, Darm – zu denken.

Publication History

Article published online:
09 March 2023

• Literatur

• 1 Perivoliotis K, Christodoulidis G, Samara AA. et al. Low-Grade Appendiceal Mucinous Neoplasm (LAMN) Primarily Diagnosed as an Ovarian Mucinous Tumor. Case Rep Surg 2021; 2021: 5523736
• 2 Borges AL, Reis-de-Carvalho C, Chorão M. et al. Low-grade mucinous appendiceal neoplasm mimicking an ovarian lesion: A case report and review of literature. World J Clin Cases 2021; 9: 2334-2343
• 3 Zhang W, Tan C, Xu M. et al. Appendiceal mucinous neoplasm mimics ovarian tumors: Challenges for preoperative and intraoperative diagnosis and clinical implication. Eur J Surg Oncol 2019; 45: 2120-2125
• 4 Cristian DA, Grama FA, Becheanu G. et al. Low-grade appendiceal mucinous neoplasm mimicking an adnexal mass. Rom J Morphol Embryol 2015; 56 (Suppl. 02) 837-842
• 5 Gok M, Topal U, Akyüz M. et al. Long-term Results of Low Grade Appendiceal Mucinous Neoplasm (LAMN): A Retrospective Analysis of 24 Patients. Arch Iran Med 2021; 24: 615-621
• 6 Fournier K, Rafeeq S, Taggart M. et al. Low-grade Appendiceal Mucinous Neoplasm of Uncertain Malignant Potential (LAMN-UMP): Prognostic Factors and Implications for Treatment and Follow-up. Ann Surg Oncol 2017; 24: 187-193
• 7 Yu XR, Mao J, Tang W. et al. Low-grade appendiceal mucinous neoplasms confined to the appendix: clinical manifestations and CT findings. J Investig Med 2020; 68: 75-81
• 8 Köhler F, Rosenfeldt M, Matthes N. et al. Incidental finding of mucinous neoplasia of the appendix: Treatment strategies. Chirurg 2019; 90: 194-201
• 9 Ceelen W, De Man M, Willaert W. et al. Incidentally found mucinous epithelial tumors of the appendix with or without pseudomyxoma peritonei: diagnostic and therapeutic algorithms based on current evidence. Acta Chir Belg 2021; 121: 225-234
• 10 McDonald JR, O’Dwyer ST, Rout S. et al. Classification of and cytoreductive surgery for low-grade appendiceal mucinous neoplasms. Br J Surg 2012; 99: 987-992
• 11 Boshnaq M, Toeima M, Hamade A. et al. Local Protocol for Management of Low-Grade Appendiceal Mucinous Neoplasm (LAMN). Indian J Surg Oncol 2020; 11: 355-359
• 12 Klag T, Wehkamp J, Bösmüller H. et al. Low-grade appendiceal mucinous neoplasm (LAMN) - 3-year endoscopic follow-up underlines benign course of LAMN type 1. Z Gastroenterol 2017; 55: 149-152
• 13 Bell PD, Huber AR, Drage MG. et al. Clinicopathologic Features of Low-grade Appendiceal Mucinous Neoplasm: A Single-institution Experience of 117 Cases. Am J Surg Pathol 2020; 44: 1549-1555
• 14 Zacharzewska-Gondek A, Szczurowska A, Guziński M. et al. A pictorial essay of the most atypical variants of the vermiform appendix position in computed tomography with their possible clinical implications. Pol J Radiol 2019; 84: e1-e8
• 15 Valasek MA, Thung I, Gollapalle E. et al. Overinterpretation is common in pathological diagnosis of appendix cancer during patient referral for oncologic care. PLoS One 2017; 12: e0179216
• 16 Matson DR, Xu J, Huffman L. et al. KRAS and GNAS Co-Mutation in Metastatic Low-Grade Appendiceal Mucinous Neoplasm (LAMN) to the Ovaries: A Practical Role for Next-Generation Sequencing. Am J Case Rep 2017; 18: 558-562
• 17 Tsai JH, Yang CY, Yuan RH. et al. Correlation of molecular and morphological features of appendiceal epithelial neoplasms. Histopathology 2019; 75: 468-477
• 18 Stewart CJ, Tsukamoto T, Cooke B. et al. Ovarian mucinous tumour arising in mature cystic teratoma and associated with pseudomyxoma peritonei: report of two cases and comparison with ovarian involvement by low-grade appendiceal mucinous tumour. Pathology 2006; 38: 534-538
• 19 Schmoeckel E, Kirchner T, Mayr D. SABT2 is supportive marker for the differentiation of a primary mucinous tumor of the ovary and an ovarian metastasis of a low-grade appendiceal mucinous neoplasm (LAMN): A series of seven cases. Pathol Res Pract 2018; 214: 426-430
• 20 Stewart CJ, Ardakani NM, Doherty DA. et al. An evaluation of the morphologic features of low-grade mucinous neoplasms of the appendix metastatic in the ovary, and comparison with primary ovarian mucinous tumors. Int J Gynecol Pathol 2014; 33: 1-10