Ophthalmologische Befunde durch Enzephalitozoon cuniculi (Stamm III) bei einem Hund

Zusammenfassung

Eine 2 Jahre alte Mischlingshündin wurde aufgrund chronischer Uveitis vorgestellt. Die Hündin stammte aus Namibia. Es konnten sowohl ein positiver Serum Antikörper-Titer als auch eine positive PCR aus dem Kammerwasser auf Enzephalitozoon cuniculi nachgewiesen werden. Am linken Auge zeigte sich eine immature anteriore fokale, kortikale Katarakt in der Peripherie mit Verdacht einer Linsenkapselruptur und deutlichen Anzeichen einer chronischen Uveitis. Am rechten Auge war eine inzipiente anteriore fokale, kortikale Katarakt sichtbar. Trotz lokaler Therapie mit nicht-steroidalen Antiphlogistika und Kortikoiden sowie einer systemischen Therapie mit Carprofen, Prednisolon und Fenbendazol kam es zu wiederkehrenden Uveitiden. Das Linsenmaterial wurde daraufhin durch Phakoemulsifikation entfernt. Die PCR des Linsenmaterials war positiv auf Enzephalitozoon cuniculi Stamm III. Das linke Auge ist durch eine erneute Uveitis mit sekundärem Glaukom 10 Monate nach der Phakoemulsifikation nicht mehr sehfähig. Beide Augen sind zum Zeitpunkt der letzten Kontrolluntersuchung (31 Monate nach der Phakoemulsifikation) reizlos und werden weiterhin entzündungshemmend behandelt. Dieses ist der erste beschriebene Fall von einem durch Enzephalitozoon cuniculi Stamm III hervorgerufenen Katarakt beim Hund.

Abstract

A 2-year-old female mixed-breed canine patient from Namibia presented originally with chronic uveitis. A serum antibody titer and a PCR test performed on the aqueous humor were positive for encephalitozoon cuniculi. The left eye showed an immature anterior focal cortical cataract in the periphery with suspected lens capsule rupture and signs of chronic uveitis. An incipient anterior focal cortical cataract was also perceivable in the patient’s right eye. Despite local treatment as well as systemic administration of carprofen, prednisolone, and fenbendazol recurrent uveitis occurred. The patient then underwent bilateral extracapsular lensextraction via phacoemulsification. A PCR test of the lens material was positive for encephalitozoon cuniculi strain III. Recurring uveitis and secondary glaucoma 10 months post-op resulted in permanent blindness of the left eye. The patient then continued to receive local anti-inflammatory treatment. The last recheck examination of both eyes, 31 month post-op, revealed no signs of uveitis. This is the first case reported of a cataract in a canine patient caused by encephalitozoon cuniculi strain III.

Schlüsselwörter

Katarakt - Mikrosporidien - Uveitis

Key words

cataract - microsporidia - uveitis

Publikationsverlauf

Eingereicht: 22. Juni 2021

Angenommen: 21. März 2022

Artikel online veröffentlicht:
14. März 2023

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