Total Synthesis of the Caged Diterpenoid Atropurpuran

Jing Xu

doi:10.1055/a-1984-0686

Synlett, Inhaltsverzeichnis

Synlett 2023; 34(04): 327-331
DOI: 10.1055/a-1984-0686

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Total Synthesis of the Caged Diterpenoid Atropurpuran

Jing Xu ∗

^aDepartment of Chemistry and Shenzhen Grubbs Institute and Guangdong Provincial Key Laboratory of Catalysis and Shenzhen Key Laboratory of Small Molecule Drug Discovery and Synthesis, Southern University of Science and Technology, Shenzhen 518055, P. R. of China

^bShenzhen Bay Laboratory, Shenzhen 518132, P. R. of China

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Abstract

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Abstract

In this account, we wish to share some stories behind our 13-step synthesis of the caged complex diterpenoid atropurpuran. Although our approach might appear to have proceeded smoothly, the unraveling of the core-construction puzzle and late-stage decorations was full of drama.

1 Introduction

2 Total Synthesis of Atropurpuran

3 Conclusion

Key words

atropurpuran - diterpenoids - total synthesis - caged natural products - ring-closing metathesis - Diels–Alder reaction

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Referenzen

References and Notes
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