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Nuklearmedizin 2023; 62(03): 220-221
DOI: 10.1055/a-2000-5589
Case Report

[68Ga]Ga-PSMA-11 uptake in planepitheliale lung cancer: a pitfall in prostate cancer imaging

[68Ga]Ga-PSMA-11 uptake in planepitheliale lung cancer: a pitfall in prostate cancer imaging
Paulina Cegla
1   Department of Endocrine Oncology and Nuclear Medicine, Maria Sklodowska-Curie National Research Institute of Oncology in Warsaw, Warszawa, Poland (Ringgold ID: RIN49585)
,
Marta Wojewodzka-Mirocha
1   Department of Endocrine Oncology and Nuclear Medicine, Maria Sklodowska-Curie National Research Institute of Oncology in Warsaw, Warszawa, Poland (Ringgold ID: RIN49585)
,
Wioletta Chalewska
1   Department of Endocrine Oncology and Nuclear Medicine, Maria Sklodowska-Curie National Research Institute of Oncology in Warsaw, Warszawa, Poland (Ringgold ID: RIN49585)
,
Marek Dedecjus
1   Department of Endocrine Oncology and Nuclear Medicine, Maria Sklodowska-Curie National Research Institute of Oncology in Warsaw, Warszawa, Poland (Ringgold ID: RIN49585)
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Prostate cancer (PCa) is the second most frequent cancer diagnosis made in men and the fifth leading cause of death worldwide [1]. Prostate-specific membrane antigen labeled with gallium 68 ([68Ga]Ga-PSMA-11) is a promising radiotracer frequently used in diagnostics of the patients with biochemical recurrence of PCa. PSMA’s expression in non-small cell lung cancer (NSCLC) ranks around 16%, while tumor neovasculature expression is seen in 59% of tumor samples and is dependent on NSCLC histopathological type. The highest (71%) is seen in large cell carcinoma (LCC) and in squamous cell carcinoma (SCC) – 64%, while the lowest (45%) is noted in adenocarcinoma (AC) [2] [3].



Publication History

Received: 12 August 2022

Accepted after revision: 15 December 2022

Article published online:
31 January 2023

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