Author commentary on David E. F. W. M. van Toledo et al.

David E. F. W. M. van Toledo et al. Appendiceal lesions in serrated polyposis patients are easily overlooked but only seldomly lead to colorectal cancer

In a retrospective cohort study including 171 patients with serrated polyposis syndrome (SPS), advanced lesions (i. e. adenocarcinoma, or serrated polyps and/or adenomas with advanced histology) were not found in surgically removed appendix specimens, nor during surveillance colonoscopy. In contrast, nonadvanced lesions were more frequently diagnosed (41.2 % and 0.9 %, respectively). These data do not support prophylactic appendectomy in patients with SPS.

Publication History

Article published online:
28 June 2023