Download PDF
Laryngorhinootologie 2023; 102(02): 104-110
DOI: 10.1055/a-2007-2002
Übersicht

COVID-19: Kollateralschäden in der Kopf-Hals-Onkologie und Präventivmaßnahmen für künftige Pandemien

COVID-19: Collateral damage in head and neck oncology and preventive measures for future pandemics
Christian Wilhelm 
1   Klinik und Poliklinik für Hals-, Nasen- und Ohrenkrankheiten, plastische und ästhetische Operationen, Universitätsklinikum Würzburg, Würzburg, Germany (Ringgold ID: RIN27207)
,
Katrin Radeloff
2   Universitätsklinik für Hals-Nasen-Ohrenheilkunde, Evangelisches Krankenhaus Oldenburg, Oldenburg, Germany
,
Agmal Scherzad
1   Klinik und Poliklinik für Hals-, Nasen- und Ohrenkrankheiten, plastische und ästhetische Operationen, Universitätsklinikum Würzburg, Würzburg, Germany (Ringgold ID: RIN27207)
,
Matthias Scheich 
1   Klinik und Poliklinik für Hals-, Nasen- und Ohrenkrankheiten, plastische und ästhetische Operationen, Universitätsklinikum Würzburg, Würzburg, Germany (Ringgold ID: RIN27207)
,
Rudolf Hagen
1   Klinik und Poliklinik für Hals-, Nasen- und Ohrenkrankheiten, plastische und ästhetische Operationen, Universitätsklinikum Würzburg, Würzburg, Germany (Ringgold ID: RIN27207)
› Author Affiliations
› Further Information
Also available at
    Permissions and Reprints

Zusammenfassung

Der Beginn der COVID-19-Pandemie führte zu enormen Herausforderungen für die globale Gesundheitsversorgung, da rasch Kapazitäten und Ressourcen für die Behandlung von COVID-19-Patienten zur Verfügung gestellt werden mussten. Dadurch kam es auch zu Einschränkungen bei der Versorgung onkologischer Patienten mit Kopf-Hals-Malignomen. Diese Übersichtsarbeit fasst die Entwicklung der Tumorinzidenzen während der Pandemie, die international erarbeiteten Richtlinien zur Versorgung von Patienten mit Kopf-Hals-Malignomen und Studien zur Verzögerung onkologischer Therapien sowie der Mortalität zusammen. Darüber hinaus werden Auswirkungen auf die psychische Gesundheit der Patienten, die psychosozialen Folgen sowie ethische Fragen beleuchtet. Perspektivisch werden Präventivmaßnahmen für derartige negative Kollateraleffekte bei künftigen Pandemien am Beispiel eines Konzepts für eine Applikationssoftware (App)-basierte digitale Betreuung von Patienten mit Kopf-Hals-Tumoren diskutiert.

Abstract

The start of the COVID-19 pandemic led to enormous challenges for global healthcare, as capacities and resources had to be made available quickly for the treatment of COVID-19 patients. As a result, restrictions had to be accepted, especially in the care of oncological patients. The collateral damage of these limitations inevitably also affects patients with head and neck cancer. This review article summarizes the development of tumor incidences during the pandemic, internationally developed guidelines for the care of patients with head and neck cancer and studies on the delay in oncological therapies and mortality. In addition, the effects on the mental health of the patients, the psychosocial consequences and ethical issues are examined. In perspective, preventive measures for such negative collateral effects in future pandemics are discussed using the example of a concept for application software (app)-based digital care for patients with head and neck cancer.

Schlüsselwörter

COVID-19-Pandemie - Kollateralschäden - Kopf-Hals-Onkologie - Therapieverzögerung - Mortalität - psychische Gesundheit - Präventivmaßnahmen - Telemedizin - digitale Lösungen - onkologische Apps

Keywords

COVID-19 pandemic - collateral damage - head and neck oncology - therapy delay - preventive measures - oncology apps


Publication History

Received: 23 May 2022

Accepted after revision: 28 December 2022

Article published online:
07 February 2023

© 2023. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

  • Literatur

  • 1 Mallah SI, Ghorab OK, Al-Salmi S. et al. COVID-19: breaking down a global health crisis. Ann Clin Microbiol Antimicrob 2021; 20: 35
    CrossrefPubMedSearch in Google Scholar
  • 2 Akande O, Akande T. COVID-19 pandemic: A global health burden. Niger Postgrad Med J 2020; 27: 147
    CrossrefPubMedSearch in Google Scholar
  • 3 Al-Quteimat OM, Amer AM. The Impact of the COVID-19 Pandemic on Cancer Patients. Am J Clin Oncol 2020; 43: 452-455
    CrossrefPubMedSearch in Google Scholar
  • 4 Liang W, Guan W, Chen R. et al. Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China. Lancet Oncol 2020; 21: 335-337
    CrossrefPubMedSearch in Google Scholar
  • 5 Liu C, Zhao Y, Okwan-Duodu D. et al. COVID-19 in cancer patients: risk, clinical features, and management. Cancer Biol Med 2020; 17: 519-527
    CrossrefPubMedSearch in Google Scholar
  • 6 Kaufman HW, Chen Z, Niles J. et al. Changes in the Number of US Patients With Newly Identified Cancer Before and During the Coronavirus Disease 2019 (COVID-19) Pandemic. JAMA Netw Open 2020; 3: e2017267
    CrossrefPubMedSearch in Google Scholar
  • 7 Voigtländer S, Hakimhashemi A, Inwald EC. et al. Auswirkungen der COVID-19-Pandemie auf die Zahl der Krebsneuerkrankungen und Krebsbehandlungen nach Tumorstadium in Bayern. Dtsch Arztebl Int 2021; 118: 660-661
    CrossrefPubMedSearch in Google Scholar
  • 8 Bakouny Z, Hawley JE, Choueiri TK. et al. COVID-19 and Cancer: Current Challenges and Perspectives. Cancer Cell 2020; 38: 629-646
    CrossrefPubMedSearch in Google Scholar
  • 9 Gascon L, Fournier I, Chiesa-Estomba C. et al. Systematic review of international guidelines for head and neck oncology management in COVID-19 patients. Eur Arch Otorhinolaryngol 2022; 279: 907-943
    CrossrefPubMedSearch in Google Scholar
  • 10 Mehanna H, Hardman JC, Shenson JA. et al. Recommendations for head and neck surgical oncology practice in a setting of acute severe resource constraint during the COVID-19 pandemic: an international consensus. Lancet Oncol 2020; 21: e350-e359
    CrossrefPubMedSearch in Google Scholar
  • 11 Salari A, Jalaeefar A, Shirkhoda M. What is the best treatment option for head and neck cancers in COVID-19 pandemic? A rapid review. Am J Otolaryngol 2020; 41: 102738
    CrossrefPubMedSearch in Google Scholar
  • 12 Brody RM, Albergotti WG, Shimunov D. et al. Changes in head and neck oncologic practice during the COVID-19 pandemic. Head Neck 2020; 42: 1448-1453
    CrossrefPubMedSearch in Google Scholar
  • 13 Ralli M, Colizza A, Cambria F. et al. Effects of COVID-19 pandemic on head and neck oncology activity: the experience of our University Hospital. Eur Rev Med Pharmacol Sci 2021; 25: 7268-7271
    CrossrefPubMedSearch in Google Scholar
  • 14 Kutikov A, Weinberg DS, Edelman MJ. et al. A War on Two Fronts: Cancer Care in the Time of COVID-19. Ann Intern Med 2020; 172: 756-758
    CrossrefPubMedSearch in Google Scholar
  • 15 Stöver T, Dazert S, Hoffmann TK. et al. Effects of the SARS-CoV-2 pandemic on the otorhinolaryngology university hospitals in the field of medical care. Laryngorhinootologie 2020; 99: 694-706
    Thieme ConnectPubMedSearch in Google Scholar
  • 16 Riemann S, Speck I, Gerstacker K. et al. Collateral damage of the COVID-19 pandemic: an alarming decline in critical procedures in otorhinolaryngology in a German university hospital. Eur Arch Oto-Rhino-Laryngology 2021; 278: 3417-3423
    CrossrefPubMedSearch in Google Scholar
  • 17 Osei E, Francis R, Mohamed A. et al. Impact of COVID-19 pandemic on the oncologic care continuum: Urgent need to restore patients care to pre-COVID-19 era. J Radiother Pract 2021; 1-11
    CrossrefPubMedSearch in Google Scholar
  • 18 Mahl C, de Melo LRS, Almeida MHA. et al. Delay in head and neck cancer care during the COVID-19 pandemic and its impact on health outcomes. Braz Oral Res 2020; 34: 1-8
    CrossrefPubMedSearch in Google Scholar
  • 19 De Luca P, Bisogno A, Colacurcio V. et al. Diagnosis and treatment delay of head and neck cancers during COVID-19 era in a tertiary care academic hospital: what should we expect?. Eur Arch Oto-Rhino-Laryngology 2021; 279: 961-965
    CrossrefPubMedSearch in Google Scholar
  • 20 Metzger K, Mrosek J, Zittel S. et al. Treatment delay and tumor size in patients with oral cancer during the first year of the COVID-19 pandemic. Head Neck 2021; 43: 3493-3497
    CrossrefPubMedSearch in Google Scholar
  • 21 Bucher S, Neumann AS, Meerwein CM. et al. Reduction of otorhinolaryngological consultations due to the COVID-19 lockdown and its impact on disease progression. Swiss Med Wkly 2021; 151: w30068
    CrossrefPubMedSearch in Google Scholar
  • 22 Hanna TP, King WD, Thibodeau S. et al. Mortality due to cancer treatment delay: systematic review and meta-analysis. BMJ 2020; 371: m4087
    CrossrefPubMedSearch in Google Scholar
  • 23 Herrmann T, Jakubek A, Trott KR. The importance of the timing of a gap in radiotherapy of squamous cell carcinomas of the head and neck. Strahlenther Onkol 1994; 170: 545-549
    PubMedSearch in Google Scholar
  • 24 Schutte HW, den Broek GB, Steens SCA. et al. Impact of optimizing diagnostic workup and reducing the time to treatment in head and neck cancer. Cancer 2020; 126: 3982-3990
    CrossrefPubMedSearch in Google Scholar
  • 25 Bardet A, Fraslin AM, Marghadi J. et al. Impact of COVID-19 on healthcare organisation and cancer outcomes. Eur J Cancer 2021; 153: 123-132
    CrossrefPubMedSearch in Google Scholar
  • 26 Ng J, Stovezky YR, Brenner DJ. et al. Development of a Model to Estimate the Association Between Delay in Cancer Treatment and Local Tumor Control and Risk of Metastases. JAMA Netw open 2021; 4: e2034065
    CrossrefPubMedSearch in Google Scholar
  • 27 Bitzer EM, Ansmann L, Hörold M. et al. „… oder doch lieber daheimbleiben?“ – Unterstützung bei der Entscheidung zur Inanspruchnahme der Regelversorgung während der COVID-19-Pandemie durch Akteure des Gesundheitssystems. Bundesgesundheitsblatt – Gesundheitsforsch – Gesundheitsschutz 2021; 64: 277-284
    CrossrefPubMedSearch in Google Scholar
  • 28 Büntzel J, Walter S, Hellmund H. et al. Auswirkungen der COVID-19-Pandemie auf die Versorgung von HNO-Tumoren – die Patientenperspektive. Laryngo-Rhino-Otologie 2021; 100: 104-110
    Thieme ConnectPubMedSearch in Google Scholar
  • 29 Büntzel J, Klein M, Keinki C. et al. Oncology services in corona times: a flash interview among German cancer patients and their physicians. J Cancer Res Clin Oncol 2020; 146: 2713-2715
    CrossrefPubMedSearch in Google Scholar
  • 30 Büntzel J, Micke O, Klein M. et al. Take care or “German Angst”? Lessons from cancer care during COVID-19 pandemic in spring 2020. J Cancer Res Clin Oncol 2021; 147: 2093-2105
    CrossrefPubMedSearch in Google Scholar
  • 31 Büssing A, Recchia DR, Hübner J. et al. Tumor patients’ fears and worries and perceived changes of specific attitudes, perceptions and behaviors due to the COVID-19 pandemic are still relevant. J Cancer Res Clin Oncol 2021; 147: 1673-1683
    CrossrefPubMedSearch in Google Scholar
  • 32 Graboyes E, Cramer J, Balakrishnan K. et al. COVID-19 pandemic and health care disparities in head and neck cancer: Scanning the horizon. Head Neck 2020; 42: 1555-1559
    CrossrefPubMedSearch in Google Scholar
  • 33 Gordin EA, Day A, Stankova L. et al. Care in the time of coronavirus: Ethical considerations in head and neck oncology. Head Neck 2020; 42: 1519-1525
    CrossrefPubMedSearch in Google Scholar
  • 34 World Health Organization. Pandemic Influenza Risk Management WHO Interim Guidance. Pandemic Influ Risk Manag 2013; 1-62 https://cdn.who.int/media/docs/default-source/documents/pandamic-influenza-risk-management.pdf
    PubMedSearch in Google Scholar
  • 35 Liang F, Guan P, Wu W. et al. A review of documents prepared by international organizations about influenza pandemics, including the 2009 pandemic: a bibliometric analysis. BMC Infect Dis 2018; 18: 383
    CrossrefPubMedSearch in Google Scholar
  • 36 Schmidt CO, Fluck J, Golebiewski M. et al. COVID-19-Forschungsdaten leichter zugänglich machen – Aufbau einer bundesweiten Informationsinfrastruktur. Bundesgesundheitsblatt – Gesundheitsforsch – Gesundheitsschutz 2021; 64: 1084-1092
    CrossrefPubMedSearch in Google Scholar
  • 37 Geraedts M, Eberlein-gonska M, Hecker R. et al. Empfehlungen für ein künftiges Pandemiemanagement. 2021; 118: 991-993
    PubMedSearch in Google Scholar
  • 38 Buhr L, Nordmeyer E, Schicktanz Si. Pandemie-Apps: Breite Akzeptanz. Dtsch Arztebl 2021; 118: 1362-1365
    PubMedSearch in Google Scholar
  • 39 Fassas S, Cummings E, Sykes KJ. et al. Telemedicine for head and neck cancer surveillance in the COVID-19 era: Promise and pitfalls. Head Neck 2021; 43: 1872-1880
    CrossrefPubMedSearch in Google Scholar
  • 40 Layfield E, Triantafillou V, Prasad A. et al. Telemedicine for head and neck ambulatory visits during COVID-19: Evaluating usability and patient satisfaction. Head Neck 2020; 42: 1681-1689
    CrossrefPubMedSearch in Google Scholar
  • 41 Prasad A, Brewster R, Newman JG. et al. Optimizing your telemedicine visit during the COVID-19 pandemic: Practice guidelines for patients with head and neck cancer. Head Neck 2020; 42: 1317-1321
    CrossrefPubMedSearch in Google Scholar
  • 42 Rak K, Völker J, Taeger J. et al. Medizinische Apps in der HNO-Heilkunde. Laryngo-Rhino-Otologie 2019; 98: S253-S289
    Thieme ConnectPubMedSearch in Google Scholar
  • 43 Kessel KA, Vogel MM, Kessel C. et al. Mobile Health in Oncology: A Patient Survey About App-Assisted Cancer Care. JMIR mHealth uHealth 2017; 5: e81
    CrossrefPubMedSearch in Google Scholar
  • 44 Duman-Lubberding S, van Uden-Kraan CF, Jansen F. et al. Feasibility of an eHealth application “OncoKompas” to improve personalized survivorship cancer care. Support Care Cancer 2016; 24: 2163-2171
    CrossrefPubMedSearch in Google Scholar
  • 45 Gomes MS, Bonan PRF, Ferreira VYN. et al. Development of a mobile application for oral cancer screening. Technol Heal Care 2017; 25: 187-195
    CrossrefPubMedSearch in Google Scholar
  • 46 Meng L, Zhao Y, Xu X. WeChat App in the follow up of thyroid cancer patients after thyroidectomy during the COVID-19 pandemic. Br J Surg 2020; 107: e533
    CrossrefPubMedSearch in Google Scholar
  • 47 Chen ZJ, Liang WT, Liu Q. et al. Use of a Remote Oncology Pharmacy Service Platform for Patients With Cancer During the COVID-19 Pandemic: Implementation and User Acceptance Evaluation. J Med Internet Res 2021; 23: e24619
    CrossrefPubMedSearch in Google Scholar
  • 48 Basch E, Deal AM, Dueck AC. et al. Overall survival results of a trial assessing patient-reported outcomes for symptom monitoring during routine cancer treatment. JAMA – J Am Med Assoc 2017; 318: 197-198
    CrossrefPubMedSearch in Google Scholar
  • 49 Teckie S, Solomon J, Kadapa K. et al. A Mobile Patient-Facing App for Tracking Patient-Reported Outcomes in Head and Neck Cancer Survivors: Single-Arm Feasibility Study. JMIR Form Res 2021; 5: e24667
    CrossrefPubMedSearch in Google Scholar
  • 50 Sprave T, Zöller D, Stoian R. et al. App-Controlled Treatment Monitoring and Support for Head and Neck Cancer Patients (APCOT): Protocol for a Prospective Randomized Controlled Trial. JMIR Res Protoc 2020; 9: e21693
    CrossrefPubMedSearch in Google Scholar
  • 51 Lu DJ, Girgis M, David JM. et al. Evaluation of Mobile Health Applications to Track Patient-Reported Outcomes for Oncology Patients: A Systematic Review. Adv Radiat Oncol 2021; 6: 100576
    CrossrefPubMedSearch in Google Scholar