SARS-CoV-2-Infektion und interstitielle Lungenerkrankungen – Positionspapier der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin

Jürgen Behr; Melanie Berger; Torsten Gerriet Blum; Francesco Bonella; Julien Dinkel; Sven Gläser; Lars Hagmeyer; Nikolaus Kneidinger; Dirk Koschel; Antje Prasse; Hortense Slevogt; Elvira Stacher-Priehse; Holger Woehrle; Michael Kreuter

doi:10.1055/a-2007-9845

Pneumologie, Table of Contents

Pneumologie 2023; 77(03): 143-157
DOI: 10.1055/a-2007-9845

Konsensuspapier

SARS-CoV-2-Infektion und interstitielle Lungenerkrankungen – Positionspapier der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin

SARS-CoV-2-Infection and Interstitial Lung Disease: Position paper of the German Respiratory Society

Jürgen Behr

¹Medizinische Klinik und Poliklinik V, LMU Klinikum der Universität München, Mitglied des Deutschen Zentrums für Lungenforschung (DZL), München, Deutschland

,

Melanie Berger

²Lungenklinik Köln-Merheim und Lehrstuhl für Pneumologie, Universität Witten/Herdecke, Kliniken der Stadt Köln gGmbH, Köln, Deutschland

,

Torsten Gerriet Blum

³Klinik für Pneumologie, Lungenklinik Heckeshorn, Helios Klinikum Emil von Behring, Berlin, Deutschland

,

Francesco Bonella

⁴Zentrum für interstitielle und seltene Lungenerkrankungen, Klinik für Pneumologie, Ruhrlandklinik, Universitätsmedizin Essen, Essen, Deutschland

,

Julien Dinkel

⁵Klinik und Poliklinik für Radiologie, LMU Klinikum der Universität München, München, Deutschland

,

Sven Gläser

⁶Klinik für Innere Medizin – Pneumologie und Infektiologie, Vivantes Klinikum Neukölln, Berlin, Deutschland

,

Lars Hagmeyer

⁷Klinik für Pneumologie und Allergologie, Krankenhaus Bethanien, Solingen, Deutschland (Ringgold ID: RIN91790)

,

Nikolaus Kneidinger

¹Medizinische Klinik und Poliklinik V, LMU Klinikum der Universität München, Mitglied des Deutschen Zentrums für Lungenforschung (DZL), München, Deutschland

,

Dirk Koschel

⁸Abteilung für Innere Medizin und Pneumologie, Fachkrankenhaus Coswig, Lungenzentrum, Coswig, Deutschland

⁹Bereich Pneumologie der Medizinischen Klinik, Carl Gustav Carus Universitätsklinik, Dresden, Deutschland

,

Antje Prasse

¹⁰Klinik für Pneumologie, Medizinische Hochschule Hannover, Hannover, Deutschland

,

Hortense Slevogt

¹¹ZIK Septomics, Universitätsklinikum Jena, Jena, Deutschland (Ringgold ID: RIN39065)

,

Elvira Stacher-Priehse

¹²Pathologisches Institut, Asklepios Fachkliniken München-Gauting, Gauting, Deutschland

,

Holger Woehrle

¹³Lungenzentrum, Lungenzentrum Ulm, Ulm, Deutschland

,

Michael Kreuter

¹⁴Zentrum für interstitielle und seltene Lungenerkrankungen, Thoraxklinik, Universitätsklinikum Heidelberg und Deutsches Zentrum für Lungenforschung, Heidelberg, Deutschland

› Author Affiliations

Abstract

Zusammenfassung

Die SARS-CoV-2-Pandemie hat in erheblichem Umfang die Diagnostik und Therapie interstitieller Lungenerkrankungen (ILD) beeinflusst. Insbesondere in der Frühphase der Pandemie und unter dem Einfluss der Delta-Variante ist es zu zahlreichen COVID-19-Pneumonien gekommen, in deren Gefolge sich bestehende interstitielle Lungenerkrankungen verschlechtert haben, neue entstanden sind oder entdeckt wurden. Den Einfluss einer SARS-CoV-2-Infektion – mit oder Viruspneumonie – auf vorbestehende ILD sowie die weitere Entwicklung neu entstandener pulmonaler Infiltrate und Konsolidierungen abzuschätzen, zu diagnostizieren und angemessen zu behandeln stellt eine nahezu tägliche Herausforderung in den interdisziplinären ILD-Boards dar. Mit diesem Positionspapier der Deutschen Gesellschaft für Pneumologie und Beatmungstherapie e.V. (DGP) werden auf Basis des aktuellen Wissensstandes Antworten auf die wichtigsten Fragestellungen gegeben.

Abstract

The SARS-CoV-2 pandemic had a tremendous impact on diagnosis and treatment of interstitial lung diseases (ILD). Especially in the early phase of the pandemic, when the delta variant was prevailling, a huge number of viral pneumonias were observed, which worsened pre-existing, triggered de novo occurence or discovery of previously subclincal interstitial lung diseases. The effect of SARS-CoV-2 infection – without or with accompanying viral pneumonia – on the further development of pre-existing ILD as well of new pulmonary inflitrates and consolidiations is difficult to predict and poses a daily challenge to interdisciplinary ILD boards. This position paper of the German Respiratory Society (DGP e.V.) provides answers to the most pressing questions based on current knowledge.

Schlüsselwörter

COVID-19 - SARS-CoV-2 - interstitielle Lungenerkrankungen - Lungenfibrose - Diagnostik und Therapie

Keywords

COVID-19 - SARS-CoV-2 - interstitial lung disease - pulmonary fibrosis - diagnosis and therapy

Full Text

References

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