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Nephrologie aktuell 2023; 27(05): 216-220
DOI: 10.1055/a-2013-6622
DOI: 10.1055/a-2013-6622
Schwerpunkt
Nephrologie
LDL-C-Senkung bei Dialysepatienten
Therapie jenseits der Evidenz?
ZUSAMMENFASSUNG
Patienten, die aufgrund einer schweren Nierenerkrankung auf eine Dialyse angewiesen sind, haben ein hohes Risiko für Herz-Kreislauf-Erkrankungen. Häufig leiden diese Patienten u. a. auch an Bluthochdruck, Fettstoffwechselstörungen oder Diabetes mellitus. Ob aber in diesem Zusammenhang die Behandlung von Dialysepatienten mit Statinen gerechtfertigt ist, ist weiterhin umstritten, da in der Vergangenheit randomisierte Studien bei diesen Patienten deren Nutzen nicht belegen konnten. Ein differenzierter Blick zeigt jedoch, dass diese Frage nicht einfach zu beantworten ist. Entgegen dem Anschein gibt es Hinweise, dass selbst Dialysepatienten noch unter bestimmten Voraussetzungen von der Therapie mit Statinen oder anderen lipidsenkenden Maßnahmen zu profitieren scheinen.
Publication History
Article published online:
08 June 2023
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