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Zeitschrift für Phytotherapie 2023; 44(02): 52-60
DOI: 10.1055/a-2039-0454
Forschung

Die Möglichkeiten der Phytotherapie bei entzündlichen Hautkrankheiten

Phytotherapy for Inflammatory Skin Diseases
Ute Wölfle
1   Forschungszentrum skintegral, Klinik für Dermatologie und Venerologie, Universitätsklinikum Freiburg, Freiburg
,
Julia Hoffmann
1   Forschungszentrum skintegral, Klinik für Dermatologie und Venerologie, Universitätsklinikum Freiburg, Freiburg
,
Christoph Schempp
1   Forschungszentrum skintegral, Klinik für Dermatologie und Venerologie, Universitätsklinikum Freiburg, Freiburg
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Zusammenfassung

In den letzten Jahren wurden einige neue pflanzliche Arzneimittel, Medizinprodukte und Hautpflegemittel für die topische Behandlung von entzündlichen Hauterkrankungen entwickelt. Besonders gut belegt ist die Wirksamkeit von Inhaltsstoffen aus dem Süßholz bei der atopischen Dermatitis und von Indigo-Extrakten bei der Psoriasis. Ein neuer vielversprechender Therapieansatz zur äußerlichen Behandlung einer geschädigten Hautbarriere sind Bitterstoffe, die an Bitterstoff-Rezeptoren der Haut binden und die Keratin- und Lipidsynthese der Keratinozyten anregen. Weitere pflanzliche Wirkstoffe für die Behandlung von Rosazea und Akne vulgaris werden ebenfalls besprochen, wie z. B. Extrakte aus dem Grüntee, der Blutwurz oder dem Hopfen.

Abstract

During the last years, several new herbal drugs, medical products and cosmetics were developed for the treatment of inflammatory skin diseases. The best studied botanicals are licorice extract for atopic dermatitis and indigo extract for psoriasis. Bitter agents are new promising active ingredients for the topical treatment of skin conditions with an impaired skin barrier. Bitter agents bind to epidermal bitter taste receptors that stimulate the formation of keratins and lipids in keratinocytes. Herbal extracts for the treatment of rosacea and acne vulgaris are also discussed, e. g., from green tea, tormentil rhizome, and hops.

Key words

Atopic dermatitis - acne - psoriasis - rosacea - gentian - indigo - licorice - frankincense

Schlüsselwörter

Atopische Dermatitis - Akne - Psoriasis - Rosazea - Enzian - Indigo - Süßholz - Weihrauch


Publication History

Article published online:
24 April 2023

© 2023. Thieme. All rights reserved.

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