CC BY 4.0 · Arch Plast Surg 2023; 50(04): 335-339
DOI: 10.1055/a-2067-5481
Cosmetic
Idea and Innovation

Lipoinjection with Adipose Stem Cells for Nasal Modeling: Rhino Cell, a Highly Versatile Alternative

1   Service of Plastic Surgery, School of Medicine and “Dr. Jose E. González” University Hospital, Autonomous University of Nuevo Leon, Monterrey, Nuevo Leon, Mexico
,
1   Service of Plastic Surgery, School of Medicine and “Dr. Jose E. González” University Hospital, Autonomous University of Nuevo Leon, Monterrey, Nuevo Leon, Mexico
,
1   Service of Plastic Surgery, School of Medicine and “Dr. Jose E. González” University Hospital, Autonomous University of Nuevo Leon, Monterrey, Nuevo Leon, Mexico
,
1   Service of Plastic Surgery, School of Medicine and “Dr. Jose E. González” University Hospital, Autonomous University of Nuevo Leon, Monterrey, Nuevo Leon, Mexico
,
1   Service of Plastic Surgery, School of Medicine and “Dr. Jose E. González” University Hospital, Autonomous University of Nuevo Leon, Monterrey, Nuevo Leon, Mexico
,
2   Laboratory of Tissue Engineering, Faculty of Medicine, University of Colima, Colima, Mexico
› Author Affiliations
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Abstract

It is undeniable that a significant number of patients who want to improve their facial appearance is increasingly interested in nonsurgical procedures. Without a doubt, the use of autologous fat could not be left out as a magnificent alternative for nasal modeling simply because of four influential factors: ease of collection, compatibility, the temporality of the results, and safety. This work describes an innovative alternative technique for nasal modeling using micrografts enriched with adipose-derived mesenchymal stem cells (ASCs). With this technique, fat was collected and divided into two samples, nanofat and microfat. Nanofat was used to isolate the ASCs; microfat was enriched with ASCs and used for nasal modeling. Lipoinjection was performed in a supraperiosteal plane on the nasal dorsum. Through a retrolabial access, the nasal tip and base of the columella were lipoinjected. We consider that nonsurgical nasal modeling using micrografts enriched with ASCs can be an attractive and innovative alternative. This technique will never be a substitute for surgical rhinoplasty. It can be performed in a minor procedure area with rapid recovery and return to the patient's daily activities the next day. If necessary, the procedure can be repeated.

Authors' Contributions

Conceptualization: Y.C.-G.; data curation: J.A.G.-G., S.E.V.-L.; formal analysis: C.M.G.C.; methodology: Y.C.-G.; project administration: H.C.-M., Y.C.-G.; visualization: V.H.C.-K.; writing, original draft: Y.C.-G., S.E.V.-L., J.A.G.-G.; writing, review, and editing: Y.C.-G., J.A.G.-G.


Ethical Approval

The study was approved by the Institutional Review Board of Universidad Autonoma de Nuevo Leon, Hospital Universitario “Dr. Jose E. Gonzalez” (registration no. CP 14-003) and performed in accordance with the principles of the Declaration of Helsinki. Written informed consents were obtained.


Patient Consent

Informed consent was obtained from the patient regarding the procedure and subsequent publication.




Publication History

Received: 23 June 2022

Accepted: 15 February 2023

Accepted Manuscript online:
01 April 2023

Article published online:
02 August 2023

© 2023. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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