Spezifische Pharmakotherapie bei intrazerebralen Blutungen unter oraler Antikoagulation

Ida Rangus; Regina von Rennenberg; Christian H Nolte

doi:10.1055/a-2073-2291

Gefäßmedizin Scan - Zeitschrift für Angiologie, Gefäßchirurgie, diagnostische und interventionelle Radiologie, Inhaltsverzeichnis

Gefäßmedizin Scan - Zeitschrift für Angiologie, Gefäßchirurgie, diagnostische und interventionelle Radiologie 2023; 10(02): 149-164
DOI: 10.1055/a-2073-2291

CME-Fortbildung

Spezifische Pharmakotherapie bei intrazerebralen Blutungen unter oraler Antikoagulation

Ida Rangus‡

¹Klinik für Neurologie mit Experimenteller Neurologie und Center for Stroke Research Berlin, Charité – Universitätsmedizin Berlin, Berlin, Deutschland

,

Regina von Rennenberg‡

²AG Klinische Schlaganfallforschung, Klinik für Neurologie, Charité-Universitätsmedizin Berlin, Berlin, Deutschland

³Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE), Bonn, Deutschland

,

Christian H Nolte

²AG Klinische Schlaganfallforschung, Klinik für Neurologie, Charité-Universitätsmedizin Berlin, Berlin, Deutschland

⁴Berlin Institute of Health (BIH), Berlin, Deutschland

⁵Deutsches Zentrum für Herz-Kreislaufforschung e.V. (DZHK), Berlin, Deutschland

› Institutsangaben

Abstract

Intrazerebrale Blutungen (ICB) gehen mit einer hohen Mortalität und Morbidität einher. Insbesondere die ICB unter oraler Antikoagulation (OAK) stellt eine therapeutische Herausforderung dar. Bei einer OAK-assoziierten ICB ist ein wesentliches Therapieziel die Wiederherstellung der Hämostase. Dieser Übersichtsartikel beschreibt die Indikationen, Anwendung und Wirksamkeit der spezifischen Gegenmittel bei ICB unter OAK anhand der aktuellen Literatur.

Schlüsselwörter

intrakranielle Blutungen - Andexanet alfa - Idarucizumab - Antagonisierung - Antikoagulanzien

Volltext

Referenzen

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