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DOI: 10.1055/a-2119-6326
Lebertransplantation – Die deutschsprachige Leitlinie der DGVS und DGAV
The German Guideline on Liver Transplantation by DGVS and DGAV
Was ist neu?
Mit der S2k-Leitlinie „Lebertransplantation“ steht erstmals eine deutschsprachige konsensbasierte Leitlinie zur Verfügung, um die Diagnostik und Therapie vor und nach Lebertransplantation zu standardisieren und zu verbessern. Ziel der Leitlinie ist es, einen Handlungskorridor für häufige klinische Entscheidungen zu etablieren, um eine konsistente und qualitativ hochwertige Patientenversorgung zu sichern.
Abstract
The S2k guideline “Liver Transplantation”, jointly developed by the German Society of Gastroenterology, Digestive and Metabolic Diseases (DGVS) and the German Society of General and Visceral Surgery (DGAV), represents the first German-language guideline for the care of adult patients before and after liver transplantation. This guideline has been crafted through a collaborative, consensus-based approach, involving experts from various disciplines. It integrates current scientific insights and clinical experience to ensure optimal care for patients undergoing liver transplantation. Targeting health care professionals in diagnostics and therapy, patient advocates, affected individuals, and their families, the guideline aims to establish a framework for common decisions in clinical practice.
Publication History
Article published online:
27 February 2024
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Literatur
- 1 Deutsche Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechsel-krankheiten (DGVS), Deutsche Gesellschaft für Allgemein- und Viszeralchirurgie (DGAV). S2k-Leitlinie „Lebertransplantation“ (Konsultationsfassung). 2023 https://register.awmf.org/assets/guidelines/021-029l_KF_S2k_Lebertransplantation_2023-01.pdf
- 2 Richtlinien zur Wartelistenführung und Organvermittlung. Bundesärztekammer. Accessed August 22, 2023 at: https://www.bundesaerztekammer.de/baek/ueber-uns/richtlinien-leitlinien-empfehlungen-und-stellungnahmen/transplantationsmedizin/wartelistenfuehrung-und-organvermittlung
- 3 Deutsche Stiftung Organtransplantation Statistiken zur Organtransplantation. Accessed August 22, 2023 at: https://dso.de/organspende/statistiken-berichte/organtransplantation
- 4 Weiler N, Schlotmann A, Schnitzbauer AA. et al. The Epidemiology of Acute Liver Failure. Dtsch Arzteblatt Int 2020; 117: 43-50
- 5 Hadem J, Tacke F, Bruns T. et al. Etiologies and outcomes of acute liver failure in Germany. Clin Gastroenterol Hepatol 2012; 10: 664-669.e2
- 6 Larsen FS, Schmidt LE, Bernsmeier C. et al. High-volume plasma exchange in patients with acute liver failure: An open randomised controlled trial. J Hepatol 2016; 64: 69-78
- 7 Maiwall R, Bajpai M, Singh A. et al. Standard-Volume Plasma Exchange Improves Outcomes in Patients With Acute Liver Failure: A Randomized Controlled Trial. Clin Gastroenterol Hepatol Off Clin Pract J Am Gastroenterol Assoc 2022; 20: e831-e854
- 8 Lee WM, Hynan LS, Rossaro L. et al. Intravenous N-acetylcysteine improves transplant-free survival in early stage non-acetaminophen acute liver failure. Gastroenterology 2009; 137: 856-864, 864.e1
- 9 Jackson WE, Malamon JS, Kaplan B. et al. Survival Benefit of Living-Donor Liver Transplant. JAMA Surg 2022;
- 10 Luo X, Leanza J, Massie AB. et al. MELD as a Metric for Survival Benefit of Liver Transplantation. Am J Transplant Off J Am Soc Transplant Am Soc Transpl Surg 2018; 18: 1231-1237
- 11 Artru F, Goldberg D, Kamath PS. Should patients with acute-on-chronic liver failure grade 3 receive higher priority for liver transplantation?. J Hepatol 2023; 78: 1118-1123
- 12 Louvet A, Labreuche J, Moreno C. et al. Early liver transplantation for severe alcohol-related hepatitis not responding to medical treatment: a prospective con-trolled study. Lancet Gastroenterol Hepatol 2022;
- 13 Loosen SH, Bock HH, Hellmich M. et al. Hospital Mortality and Current Trends in Liver Transplantation in Germany – a Systematic Analysis of Standardized Hospital Discharge Data, 2008–2017. Dtsch Arzteblatt Int 2021; 118: 497-502
- 14 Mazzaferro V, Citterio D, Bhoori S. et al. Liver transplantation in hepatocellular carcinoma after tumour downstaging (XXL): a randomised, controlled, phase 2b/3 trial. Lancet Oncol 2020; 21: 947-956
- 15 Germani G, Zeni N, Zanetto A. et al. Influence of donor and recipient gender on liver transplantation outcomes in Europe. Liver Int 2020; 40: 1961-1971
- 16 Nijboer A, Ulrich F, Bechstein WO. et al. Volume and outcome relation in Ger-man liver transplant centers: what lessons can be learned?. Transplant Res 2014; 3: 5
- 17 Baganate F, Beal EW, Tumin D. et al. Early mortality after liver transplantation: Defining the course and the cause. Surgery 2018; 164: 694-704
- 18 Darstein F, Zimmermann T, Lang H. Langzeitkomplikationen nach viszeraler Organtransplantation. Die Gastroenterologie 2019; 14: 296-300