Chromatic Pupillometry – a New Technique for Assessing Function in Glaucoma?

Abstract

Chromatic pupillometry allows quantification of photoreceptor-driven (extrinsic) and melanopsin-driven (intrinsic) responses of the intrinsic-photosensitive retinal ganglion cells (ipRGCs). This small subpopulation of retinal ganglion cells is also affected by glaucoma, making chromatic pupillometry a potential diagnostic tool. Studies show reduced phasic and tonic responses in glaucoma patients. The diagnostic value in earlier studies depended on the technical details and the study design. The purpose of this article is to give an introduction into the principles of chromatic pupillometry and to discuss the potential applications in the management of glaucoma.

Key words

glaucoma - pupillometry - retinal ganglion cells - neuroophthalmology

Publication History

Received: 20 June 2023

Accepted: 04 July 2023

Article published online:
07 September 2023

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