Modernes Asthma-Management

Die Ziele einer modernen Asthma-Therapie sind die Symptomprävention und die Asthma-Remission. Die diagnostische Voraussetzung hierfür ist die Phänotypisierung der Patienten. Dieser Beitrag stellt die 3 darauf basierenden Säulen des modernen Asthma-Managements vor: Basismaßnahmen (wie Schulung und Vermeidung von Asthma-Triggern), die Therapie mit DMAADs („disease-modifying anti-asthmatic drugs“) und die Behandlung von Komorbiditäten.

Abstract

Symptom prevention and remission are the goals of asthma treatment. Precise phenotyping of the patients, including history, lung function, allergology and measurement of type 2 biomarkers, is the essential prerequisite for treatment success. Basic measures, treatment with DMAADs („disease-modifying anti-asthmatic drugs“: predominantly inhaled corticosteroids, biologics, and allergen immunotherapy) and treatment of comorbidities are the cornerstones of modern asthma management. The treatment of upper airway diseases such as allergic rhinitis (often associated with early-onset asthma) or chronic rhinosinusitis (often associated with adult-onset asthma, with 2 forms: either with nasal polyps, CRSwNP, or without nasal polyps, CRSsNP) is of major importance in this regard.

Kernaussagen

• Ziel einer modernen Asthma-Therapie ist die Symptomprävention und das Erreichen einer Asthma-Remission.

• Die genaue Patienten-Phänotypisierung (Anamnese-Erhebung, Lungenfunktionsprüfung, allergologische Diagnostik, Biomarker-Messung) ist Voraussetzung für den Therapieerfolg.

• Das moderne Asthma-Management besteht aus Basismaßnahmen, der Therapie mit DMAADs – v.a. inhalative Steroide, Allergen-Immuntherapien und Biologika – sowie der Behandlung von Komorbiditäten wie allergischer Rhinitis oder chronischer Rhinosinusitis.

Schlüsselwörter

Asthma - DMAADs - Rhinitis - chronische Rhinosinusitis - Remission

Keywords

asthma - DMAADs - rhinitis - chronic rhinosinusitis - remission

Publication History

Article published online:
11 June 2024

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