Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000142.xml
Frauenheilkunde up2date 2024; 18(03): 193-199
DOI: 10.1055/a-2164-9444
DOI: 10.1055/a-2164-9444
SOP/Arbeitsablauf
SOP Therapieassoziierte Anämie
Die Anämie ist ein häufig vorkommendes Krankheitsbild bei Patienten mit Tumorerkrankungen, insbesondere unter tumorspezifischer Therapie. Mit der Differenzialdiagnostik und gezielten therapeutischen Optionen sollte der behandelnde Mediziner vertraut sein. Zum Thema der tumor- und therapieassoziierten Anämie soll der Artikel einen Überblick und Handlungsempfehlungen geben.
Publication History
Article published online:
12 June 2024
© 2024. Thieme. All rights reserved.
Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany
-
Literatur
- 1 Knight K, Wade S, Balducci L. Prevalence and outcomes of anemia in cancer: a systematic review of the literature. Am J Med 2004; 116(Suppl. 7A): 11S-26S DOI: 10.1016/j.amjmed.2003.12.008. (PMID: 15050883)
- 2 Ludwig H, Van Belle S, Barrett-Lee P. et al. The European Cancer Anaemia Survey (ECAS): a large, multinational, prospective survey defining the prevalence, incidence, and treatment of anaemia in cancer patients. Eur J Cancer 2004; 40: 2293-2306 DOI: 10.1016/j.ejca.2004.06.019. (PMID: 15454256)
- 3 Harrison LB, Shasha D, White C. et al. Radiotherapy-associated anemia: the scope of the problem. Oncologist 2000; 5 (Suppl. 2) 1-7 DOI: 10.1634/theoncologist.5-suppl_2-1. (PMID: 10896322)
- 4 Onkopedia. Eisenmangel und Eisenmangelanämie. 2022 Accessed February 05, 2024 at: https://www.onkopedia.com/de/onkopedia/guidelines/eisenmangel-und-eisenmangelanaemie/@@guideline/html/index.html
- 5 Hahn J-M. Checkliste Innere Medizin. 9. Aufl.. Stuttgart: Thieme; 2023
- 6 Medizinische Laboratorien Düsseldorf. Erythropoetin (EPO). Accessed February 05, 2024 at: https://www.labor-duesseldorf.de/examination/view/erythropoetin-epo
- 7 Weiss G, Goodnough LT. Anemia of chronic disease. N Engl J Med 2005; 352: 1011-1023 DOI: 10.1056/NEJMra041809. (PMID: 15758012)
- 8 Miller CB, Jones RJ, Piantadosi S. et al. Decreased erythropoietin response in patients with the anemia of cancer. N Engl J Med 1990; 322: 1689-1692 DOI: 10.1056/NEJM199006143222401. (PMID: 2342534)
- 9 Fleming RE, Bacon BR. Orchestration of iron homeostasis. N Engl J Med 2005; 352: 1741-1744 DOI: 10.1056/NEJMp048363. (PMID: 15858181)
- 10 Ganz T. Hepcidin and iron regulation, 10 years later. Blood 2011; 117: 4425-4433 DOI: 10.1182/blood-2011-01-258467. (PMID: 21346250)
- 11 Kautz L, Jung G, Nemeth E. et al. The erythroid factor erythroferrone and its role in iron homeostasis. Blood 2013; 122: 4 DOI: 10.1182/blood.V122.21.4.4.
- 12 Alkhateeb AA, Connor JR. The significance of ferritin in cancer: anti-oxidation, inflammation and tumorigenesis. Biochim Biophys Acta 2013; 1836: 245-254 DOI: 10.1016/j.bbcan.2013.07.002. (PMID: 23891969)
- 13 Ludwig H, Müldür E, Endler G. et al. Prevalence of iron deficiency across different tumors and its association with poor performance status, disease status and anemia. Ann Oncol 2013; 24: 1886-1892 DOI: 10.1093/annonc/mdt118. (PMID: 23567147)
- 14 Henry DH, Dahl NV, Auerbach M. et al. Intravenous ferric gluconate significantly improves response to epoetin alfa versus oral iron or no iron in anemic patients with cancer receiving chemotherapy. Oncologist 2007; 12: 231-242 DOI: 10.1634/theoncologist.12-2-231. (PMID: 17296819)
- 15 Auerbach M, Ballard H, Trout JR. et al. Intravenous iron optimizes the response to recombinant human erythropoietin in cancer patients with chemotherapy-related anemia: a multicenter, open-label, randomized trial. J Clin Oncol 2004; 22: 1301-1307 DOI: 10.1200/JCO.2004.08.119. (PMID: 15051778)
- 16 Macciò A, Madeddu C, Gramignano G. et al. Efficacy and safety of oral lactoferrin supplementation in combination with rHuEPO-beta for the treatment of anemia in advanced cancer patients undergoing chemotherapy: open-label, randomized controlled study. Oncologist 2010; 15: 894-902 DOI: 10.1634/theoncologist.2010-0020. (PMID: 20647390)
- 17 Steensma DP, Sloan JA, Dakhil SR. et al. Phase III, randomized study of the effects of parenteral iron, oral iron, or no iron supplementation on the erythropoietic response to darbepoetin alfa for patients with chemotherapy-associated anemia. J Clin Oncol 2011; 29: 97-105 DOI: 10.1200/JCO.2010.30.3644. (PMID: 21098317)
- 18 Steinmetz T, Tschechne B, Harlin O. et al. Clinical experience with ferric carboxymaltose in the treatment of cancer- and chemotherapy-associated anaemia. Ann Oncol 2013; 24: 475-482 DOI: 10.1093/annonc/mds338. (PMID: 23071262)
- 19 Tonia T, Mettler A, Robert N. et al. Erythropoietin or darbepoetin for patients with cancer. Cochrane Database Syst Rev 2012; (12) CD003407 DOI: 10.1002/14651858.CD003407.pub5. (PMID: 23235597)
- 20 Cella D, Eton DT, Lai JS. et al. Combining anchor and distribution-based methods to derive minimal clinically important differences on the Functional Assessment of Cancer Therapy (FACT) anemia and fatigue scales. J Pain Symptom Manage 2002; 24: 547-561 DOI: 10.1016/s0885-3924(02)00529-8. (PMID: 12551804)
- 21 Leitlinienprogramm Onkologie (Deutsche Krebsgesellschaft, Deutsche Krebshilfe, AWMF). S3-Leitlinie Supportive Therapie bei onkologischen PatientInnen. AWMF-Registernummer: 032/054OL. 2020. Accessed March 11, 2024 at: https://www.leitlinienprogramm-onkologie.de/leitlinien/supportive-therapie/
- 22 Moebus V, Jackisch C, Schneeweiss A. AGO Breast Study Group. et al. Adding epoetin alfa to intense dose-dense adjuvant chemotherapy for breast cancer: randomized clinical trial. J Natl Cancer Inst 2013; 105: 1018-1026 DOI: 10.1093/jnci/djt145. (PMID: 23860204)
- 23 Nitz U, Gluz O, Zuna I. West German Study Group. et al. Final results from the prospective phase III WSG-ARA trial: impact of adjuvant darbepoetin alfa on event-free survival in early breast cancer. Ann Oncol 2014; 25: 75-80 DOI: 10.1093/annonc/mdt505. (PMID: 24356620)
- 24 McFarland JG. Perioperative blood transfusions: indications and options. Chest 1999; 115 (Suppl. 5) 113S-121S DOI: 10.1378/chest.115.suppl_2.113s. (PMID: 10331343)
- 25 Aapro M, Beguin Y, Bokemeyer C. et al. Management of anaemia and iron deficiency in patients with cancer: ESMO Clinical Practice Guidelines. Ann Oncol 2018; 29 (Suppl. 4) iv271 DOI: 10.1093/annonc/mdy323. (PMID: 30285221)
- 26 Rizzo JD, Brouwers M, Hurley P. et al. American Society of Clinical Oncology/American Society of Hematology clinical practice guideline update on the use of epoetin and darbepoetin in adult patients with cancer. J Clin Oncol 2010; 28: 4996-5010 DOI: 10.1200/JCO.2010.29.2201. (PMID: 20975064)
- 27 Hicks LK, Bering H, Carson KR. et al. The ASH Choosing Wisely® campaign: five hematologic tests and treatments to question. Blood 2013; 122: 3879-3883 DOI: 10.1182/blood-2013-07-518423.
- 28 Aapro M, Beguin Y, Bokemeyer C. et al. Management of anaemia and iron deficiency in patients with cancer: ESMO Clinical Practice Guidelines. Ann Oncol 2018; 29: iv96-iv110 DOI: 10.1093/annonc/mdx758. (PMID: 29471514)
- 29 Onkopedia-Leitlinie. Empfehlungen der Fachgesellschaft zur Diagnostik und Therapie hämatologischer und onkologischer Erkrankungen. 2018.
- 30 Link H, Schmitz S. Treatment of cancer-associated anaemia: results from a two-day cross-sectional survey in Germany. Onkologie 2013; 36: 266-272 DOI: 10.1159/000350306. (PMID: 23689221)