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DOI: 10.1055/a-2198-0684
Nonosseous bone seeking tracer focal uptake in the conventional scintigraphy
Extraskelettaler fokaler Knochentraceruptake in der konventionellen Szintigrafie![](https://www.thieme-connect.de/media/10.1055-s-00034924/202401/lookinside/thumbnails/10-1055-a-2198-0684-1.jpg)
Scintigraphy with bone-seeking tracers is used frequently for evaluation of focal abnormalities of bone metabolism. Tracer uptake depends on multiple physiological and pathological factors. For tracer uptake in extra-osseous tissues multiple etiologies are described. In patients showing intra-pulmonary uptake of bone-seeking tracers, exact differentiation of the etiology is mandatory for trageted therapy. In this case by fusion technique of CT and SPECT images 2 focal intra-pulmonary hot spots were localized in pulmonary arteries in a prostate cancer patient.
Publication History
Received: 05 October 2023
Accepted: 25 October 2023
Article published online:
22 November 2023
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References
- 1 Soundarajan R, Naswa N, Sharma P. et al. SPECT/CT for characterization of extraosseous uptake of 99mTc-methylene diphosphonate on bone scintigraphy. Diagn Interv Radiol 2013; 19: 405-410
- 2 Agraval A, Purandare N, Shah S. et al. Metastatic mimics on bone scan:” All that glitters is not metastatic. Indian J Nuc Med 2016; 31: 185-190
- 3 Peller PJ, Ho VB, Kransdorf MJ. Extraosseous Tc-99m MDP uptake: a pathologic approach. RadioGraphics 1993; 13: 715-734
- 4 Loutfi I, Collier BD, Mohammed AM. Nonosseous abnormalities on bone scans. J Nucl Med Technol 2003; 31: 149-143 (PMID: 12968045)
- 5 Wale DJ, Wong KK, Savas H. et al. Extraosseous findings on bone scintigraphy using fusion SPECT/CT and correlative imaging. ARJ 2015; 205: 160-172 DOI: 10.2214/AJR.14.13914. (PMID: 26102395)
- 6 Zuckier LS, Martineau P. Altered biodistribution of radiopharmaceuticals used in bone scintigraphy. Sem Nucl Med 2015; 45: 81-96 DOI: 10.1053/j.semnuclmed.2014.07.007. (PMID: 25475381)
- 7 Gnanasegaran G, Cook G, Adamson K. et al. Pattern variants, artifacts, and pitfalls in conventional radionuclide bone imaging and SPECT/CT. Sem Nucl Med 2009; 39: 380-395
- 8 Pasquier M, Schaller MD, Abdou M. et al. Les calcifications pulmonaires métastatiques. Rev Mal Respir 2012; 29: 775-784
- 9 Rosenthal DI, Chandler HL, Azizi F. et al. Uptake of bone imaging agent by diffuse pulmonary metastatic calcification. Am J Roentgenol 1977; 128: 871-874
- 10 Hung JC, Ponto JA, Hammes RJ. Radiopharmaceutical-related pitfalls and artifacts. Sem Nucl Med 1996; 26: 208-255 DOI: 10.1016/s0001-2998(96)80002-x. (PMID: 8916315)
- 11 Ceylan Gunay E, Erdogan A, Apaydin D. Unusual extraosseous tumoral accumulation of 99mTc-MDP in non-Hodgkin´s lymphoma in two cases. Rev Esp Med Nucl 2011; 30: 162-164 DOI: 10.1016/j.remn.2010.04.012. (PMID: 20580467)
- 12 Tantum JL, Burke TS, Hirsch JI. et al. Artifactual focal accumulation of Tc-99m bone imaging tracer in chest – technical note (bone imaging artifact. Clin Nucl Med 1984; 10: 16-18