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Osteologie 2024; 33(01): 21-24
DOI: 10.1055/a-2217-2869
Review

Einfluss von andauerndem Schmerz und Medikamenten auf das Sturz- und Frakturrisiko

Influence of Persistent Pain and Drugs on Falls and Fracture Risk
Helmut Frohnhofen 
1   Orthopädie und Unfallchirurgie, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany
,
Carla Stenmanns
3   Klinik für Orthopädie und Unfallchirurgie, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany
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Zusammenfassung

Die Prävalenz von Schmerzen steigt mit dem Alter, ebenso wie die Anzahl der gleichzeitig vorliegenden Erkrankungen. Diese Multimorbidität triggert zudem die Verordnung zahlreicher Medikamente. Diese sog. Polypharmazie oder die Verordnung bestimmter Medikamentengruppen wie Analgetika, Hypnotika oder Antidepressiva sind mit der Häufigkeit von Sturzereignissen und Frakturen assoziiert. Diese Assoziation verleitet dazu, durch eine Reduktion der Anzahl der verordneten Medikamente ungünstige Ereignisse zu verhindern. Die Evidenz für diesen Ansatz konnte in randomisierten Studien jedoch nicht erbracht werden. Das Management der Medikation im Alter erfordert eine klare Indikation für ein Präparat, die regelmäßige Überprüfung dieser Indikation und die Auswahl des am besten verträglichen Präparates.

Abstract

The prevalence of pain increases with age, as does the number of co-existing diseases. This multimorbidity also triggers the prescription of numerous drugs. This so-called polypharmacy or the prescription of certain groups of drugs such as analgesics, hypnotics or antidepressants are associated with the frequency of falls and fractures. This association leads to the idea to prevent adverse events by reducing the number of drugs prescribed. However, the evidence for this approach could not be provided in randomized studies. Medication management in old age requires a clear indication for a drug, regular review of this indication, and selection of the most well-tolerated drug.

Schlüsselwörter

Andauernder Schmerz - Polypharmazie - Sturzereignisse - Frakturen - höheres Lebensalter

Key words

Persistent pain - polypharmacy - falls - fractures - advanced age


Publication History

Received: 11 September 2023

Accepted: 21 November 2023

Article published online:
20 February 2024

© 2024. Thieme. All rights reserved.

Georg Thieme Verlag
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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