Efficient Preparation of O-Isopropylidene Derivatives of Carbohydrates Catalyzed by Sulfonated Graphene (GR-SO₃H) as a Sustainable Acid Catalyst

Abstract

Sulfonated graphene (GR-SO₃H) has emerged as a mild, efficient and sustainable catalyst for the preparation of O-isopropylidene derivatives of unprotected and anomeric-protected carbohydrates with acetone and 2,2-dimethoxypropane at room temperature. This methodology not only provides excellent yields but also reduces reaction times, and it demonstrates exceptional recyclability, allowing the catalyst to be reused multiple times.

Key words

acetone - carbohydrates - 2,2-dimethoxypropane - GR-SO₃H - O-isopropylidene acetals - sustainability

• References

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