J Knee Surg
DOI: 10.1055/a-2232-7657
Original Article

Preoperative and Postoperative Weight Change has Minimal Influence on Health Care Utilization and Patient-Reported Outcomes Following Total Knee Arthroplasty

Joshua L. Tidd
1   Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, Ohio
2   College of Medicine, Northeast Ohio Medical University, Rootstown, Ohio
,
1   Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, Ohio
,
Precious C. Oyem
1   Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, Ohio
3   Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio
,
Ignacio Pasqualini
1   Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, Ohio
,
Matthew J. Hadad
1   Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, Ohio
,
Alison K. Klika
1   Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, Ohio
,
Matthew E. Deren
1   Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, Ohio
,
1   Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, Ohio
› Author Affiliations

Abstract

As obesity becomes more prevalent, more patients are at risk of lower extremity osteoarthritis and subsequent total knee arthroplasty (TKA). This study aimed to test (1) the association of preoperative weight change with health care utilization and (2) the association of pre- and postoperative weight changes with failure to achieve satisfaction and minimal clinically important difference (MCID) in Knee injury and Osteoarthritis Outcome Score for pain (KOOS-Pain) and function (KOOS-PS) 1 year after TKA. Prospectively collected monocentric data on patients who underwent primary TKA were retrospectively reviewed. Multivariable logistic regression assessed the influence of BMI and weight change on outcomes while controlling for confounding variables. Outcomes included prolonged length of stay (LOS >3 days), nonhome discharge, 90-day readmission rate, satisfaction, and achievement of MCID for KOOS-Pain and KOOS-PS. Preoperative weight change had no impact on prolonged LOS (gain, p = 0.173; loss, p = 0.599). Preoperative weight loss was associated with increased risk of nonhome discharge (odds ratio [OR]: 1.47, p = 0.003). There was also increased risk of 90-day readmission with preoperative weight gain (OR: 1.27, p = 0.047) and decreased risk with weight loss (OR: 0.73, p = 0.033). There was increased risk of nonhome discharge with obesity class II (OR: 1.6, p = 0.016) and III (OR: 2.21, p < 0.001). Weight change was not associated with failure to achieve satisfaction, MCID in KOOS-Pain, or MCID in KOOS-PS. Obesity class III patients had decreased risk of failure to reach MCID in KOOS-Pain (OR: 0.43, p = 0.005) and KOOS-PS (OR: 0.7, p = 0.007). Overall, pre- and postoperative weight change has little impact on the achievement of satisfaction and clinically relevant differences in pain and function at 1 year. However, preoperative weight gain was associated with a higher risk of 90-day readmissions after TKA. Furthermore, patients categorized in Class III obesity were at increased risk of nonhome discharge but experienced a greater likelihood of achieving MCID in KOOS-Pain and KOOS-PS. Our results raise awareness of the dangers of using weight changes and BMI alone as a measure of TKA eligibility.



Publication History

Received: 10 October 2023

Accepted: 18 December 2023

Accepted Manuscript online:
19 December 2023

Article published online:
23 January 2024

© 2024. Thieme. All rights reserved.

Thieme Medical Publishers, Inc.
333 Seventh Avenue, 18th Floor, New York, NY 10001, USA

 
  • References

  • 1 Jester R, Rodney A. The relationship between obesity and primary total knee replacement: a scoping review of the literature. Int J Orthop Trauma Nurs 2021; 42: 100850
  • 2 Finucane MM, Stevens GA, Cowan MJ. et al; Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group (Body Mass Index). National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9·1 million participants. Lancet 2011; 377 (9765): 557-567
  • 3 Lohmander LS, Gerhardsson de Verdier M, Rollof J, Nilsson PM, Engström G. Incidence of severe knee and hip osteoarthritis in relation to different measures of body mass: a population-based prospective cohort study. Ann Rheum Dis 2009; 68 (04) 490-496
  • 4 Nho SJ, Kymes SM, Callaghan JJ, Felson DT. The burden of hip osteoarthritis in the United States: epidemiologic and economic considerations. J Am Acad Orthop Surg 2013; 21 (Suppl. 01) S1-S6
  • 5 Vasarhelyi EM, MacDonald SJ. The influence of obesity on total joint arthroplasty. J Bone Joint Surg Br 2012; 94 (11, Suppl A): 100-102
  • 6 Rullán PJ, Deren ME, Zhou G. et al. The arthroplasty surgeon growth indicator: a tool for monitoring supply and demand trends in the orthopaedic surgeon workforce from 2020 to 2050. J Bone Joint Surg Am 2023; 105 (13) 1038-1045
  • 7 Alvi HM, Mednick RE, Krishnan V, Kwasny MJ, Beal MD, Manning DW. The effect of BMI on 30 day outcomes following total joint arthroplasty. J Arthroplasty 2015; 30 (07) 1113-1117 DOI: 10.1016/j.arth.2015.01.049.
  • 8 Järvenpää J, Kettunen J, Kröger H, Miettinen H. Obesity may impair the early outcome of total knee arthroplasty. Scand J Surg 2010; 99 (01) 45-49
  • 9 DeMik DE, Bedard NA, Dowdle SB. et al. Complications and obesity in arthroplasty—a hip is not a knee. J Arthroplasty 2018; 33 (10) 3281-3287
  • 10 Rhoads C, Emara AK, Pumo T. et al. What are the drivers of readmission for serious venous thromboembolic events after primary total knee arthroplasty? An analysis of 862,915 patients. J Knee Surg 2023; 36 (11) 1141-1149
  • 11 Hanly RJ, Marvi SK, Whitehouse SL, Crawford RW. Morbid obesity in total hip arthroplasty: redefining outcomes for operative time, length of stay, and readmission. J Arthroplasty 2016; 31 (09) 1949-1953
  • 12 Raphael IJ, Parmar M, Mehrganpour N, Sharkey PF, Parvizi J. Obesity and operative time in primary total joint arthroplasty. J Knee Surg 2013; 26 (02) 95-99
  • 13 Turcotte J, Kelly M, Aja J, King P, MacDonald J. Complication rates and resource utilization after total hip and knee arthroplasty stratified by body mass index. J Orthop 2021; 24: 111-120
  • 14 Kim BI, Cochrane NH, O'Donnell JA. et al. Preoperative weight loss and postoperative weight gain independently increase risk for revision after primary total knee arthroplasty. J Arthroplasty 2022; 37 (04) 674-682
  • 15 Mackie A, Muthumayandi K, Shirley M, Deehan D, Gerrand C. Association between body mass index change and outcome in the first year after total knee arthroplasty. J Arthroplasty 2015; 30 (02) 206-209
  • 16 Polat G, Ceylan HH, Sayar S, Kucukdurmaz F, Erdil M, Tuncay I. Effect of body mass index on functional outcomes following arthroplasty procedures. World J Orthop 2015; 6 (11) 991-995
  • 17 Stock LA, Brennan JC, Turcotte JJ, King PJ. Effect of weight change on patient-reported outcomes following total joint arthroplasty. J Arthroplasty 2022; 37 (10) 1991-1997.e1
  • 18 Blankstein M, Browne JA, Sonn KA, Ashkenazi I, Schwarzkopf R. Go big or go home: obesity and total joint arthroplasty. J Arthroplasty 2023; 38 (10) 1928-1937
  • 19 Seward MW, Chen AF. Obesity, preoperative weight loss, and telemedicine before total joint arthroplasty: a review. Arthroplasty 2022; 4 (01) 2
  • 20 Inacio MC, Kritz-Silverstein D, Raman R. et al. The impact of pre-operative weight loss on incidence of surgical site infection and readmission rates after total joint arthroplasty. J Arthroplasty 2014; 29 (03) 458-64.e1
  • 21 Orr MN, Klika AK, Emara AK, Piuzzi NS. Cleveland Clinic Arthroplasty Group. Combinations of preoperative patient-reported outcome measure phenotype (pain, function, and mental health) predict outcome after total knee arthroplasty. J Arthroplasty 2022; 37 (6S): S110 , 120.e5
  • 22 Orr MN, Klika AK, Emara AK, Piuzzi NS. Cleveland Clinic Arthroplasty Group. Dissatisfaction after total hip arthroplasty associated with preoperative patient-reported outcome phenotypes. J Arthroplasty 2022; 37 (7S): S498-S509
  • 23 Orthopaedics OMECC. OME Cleveland Clinic Orthopaedics. Implementing a scientifically valid, cost-effective, and scalable data collection system at point of care: The Cleveland Clinic OME Cohort. J Bone Joint Surg Am 2019; 101 (05) 458-464
  • 24 Kind AJH, Buckingham WR. Making neighborhood-disadvantage metrics accessible—the neighborhood atlas. N Engl J Med 2018; 378 (26) 2456-2458
  • 25 Ast MP, Abdel MP, Lee YY, Lyman S, Ruel AV, Westrich GH. Weight changes after total hip or knee arthroplasty: prevalence, predictors, and effects on outcomes. J Bone Joint Surg Am 2015; 97 (11) 911-919
  • 26 Mihalko WM, Bergin PF, Kelly FB, Canale ST. Obesity, orthopaedics, and outcomes. J Am Acad Orthop Surg 2014; 22 (11) 683-690
  • 27 Kuo AC, Giori NJ, Bowe TR. et al. Comparing methods to determine the minimal clinically important differences in patient-reported outcome measures for veterans undergoing elective total hip or knee arthroplasty in veterans health administration hospitals. JAMA Surg 2020; 155 (05) 404-411
  • 28 Lyman S, Lee YY, McLawhorn AS, Islam W, MacLean CH. What are the minimal and substantial improvements in the HOOS and KOOS and JR versions after total joint replacement?. Clin Orthop Relat Res 2018; 476 (12) 2432-2441
  • 29 Workgroup of the American Association of Hip and Knee Surgeons Evidence Based Committee. Obesity and total joint arthroplasty: a literature based review. J Arthroplasty 2013; 28 (05) 714-721
  • 30 Godziuk K, Prado CM, Beaupre L, Jones CA, Werle JR, Forhan M. A critical review of weight loss recommendations before total knee arthroplasty. Joint Bone Spine 2021; 88 (02) 105114
  • 31 Laperche J, Feinn R, Myrick K, Halawi MJ. Obesity and total joint arthroplasty: Does weight loss in the preoperative period improve perioperative outcomes?. Arthroplasty 2022; 4 (01) 47
  • 32 Inacio MC, Kritz-Silverstein D, Raman R. et al. The risk of surgical site infection and re-admission in obese patients undergoing total joint replacement who lose weight before surgery and keep it off post-operatively. Bone Joint J 2014; 96-B (05) 629-635
  • 33 Seward MW, Briggs LG, Bain PA, Chen AF. Preoperative nonsurgical weight loss interventions before total hip and knee arthroplasty: a systematic review. J Arthroplasty 2021; 36 (11) 3796-3806.e8
  • 34 Dowsey MM, Brown WA, Cochrane A, Burton PR, Liew D, Choong PF. Effect of bariatric surgery on risk of complications after total knee arthroplasty: a randomized clinical trial. JAMA Netw Open 2022; 5 (04) e226722
  • 35 Nearing II EE, Santos TM, Topolski MS, Borgert AJ, Kallies KJ, Kothari SN. Benefits of bariatric surgery before elective total joint arthroplasty: is there a role for weight loss optimization?. Surg Obes Relat Dis 2017; 13 (03) 457-462
  • 36 Stambough JB. In patients with knee OA and severe obesity, bariatric surgery and weight loss before TKA reduced complications versus TKA alone. J Bone Joint Surg Am 2023; 105 (10) 805
  • 37 Ryan SP, Couch CG, Duong SQ. et al. Does bariatric surgery prior to primary total knee arthroplasty improve outcomes?. J Arthroplasty 2022; 37 (6S): S165-S169
  • 38 Meller MM, Goodman S, Gonzalez MH, Lau E. Does bariatric surgery normalize risks after total knee arthroplasty? Administrative Medicare data. J Am Acad Orthop Surg Glob Res Rev 2019; 3 (12) e19.00102
  • 39 Keeney BJ, Austin DC, Jevsevar DS. Preoperative weight loss for morbidly obese patients undergoing total knee arthroplasty: determining the necessary amount. J Bone Joint Surg Am 2019; 101 (16) 1440-1450
  • 40 Khow YZ, Goh GS, Chen JY, Lo NN, Yeo SJ, Liow MHL. Change in body mass index after simultaneous bilateral total knee arthroplasty: risk factors and its influence on functional outcomes. J Arthroplasty 2021; 36 (06) 1974-1979
  • 41 Baker P, Muthumayandi K, Gerrand C, Kleim B, Bettinson K, Deehan D. Influence of body mass index (BMI) on functional improvements at 3 years following total knee replacement: a retrospective cohort study. PLoS One 2013; 8 (03) e59079
  • 42 Collins JE, Donnell-Fink LA, Yang HY. et al. Effect of obesity on pain and functional recovery following total knee arthroplasty. J Bone Joint Surg Am 2017; 99 (21) 1812-1818
  • 43 Prohaska MG, Keeney BJ, Beg HA. et al. Preoperative body mass index and physical function are associated with length of stay and facility discharge after total knee arthroplasty. Knee 2017; 24 (03) 634-640
  • 44 Kerkhoffs GM, Servien E, Dunn W, Dahm D, Bramer JA, Haverkamp D. The influence of obesity on the complication rate and outcome of total knee arthroplasty: a meta-analysis and systematic literature review. J Bone Joint Surg Am 2012; 94 (20) 1839-1844
  • 45 McElroy MJ, Pivec R, Issa K, Harwin SF, Mont MA. The effects of obesity and morbid obesity on outcomes in TKA. J Knee Surg 2013; 26 (02) 83-88
  • 46 Boyce L, Prasad A, Barrett M. et al. The outcomes of total knee arthroplasty in morbidly obese patients: a systematic review of the literature. Arch Orthop Trauma Surg 2019; 139 (04) 553-560
  • 47 Pozzobon D, Ferreira PH, Blyth FM, Machado GC, Ferreira ML. Can obesity and physical activity predict outcomes of elective knee or hip surgery due to osteoarthritis? A meta-analysis of cohort studies. BMJ Open 2018; 8 (02) e017689
  • 48 Evans JT, Mouchti S, Blom AW. et al. Obesity and revision surgery, mortality, and patient-reported outcomes after primary knee replacement surgery in the National Joint Registry: a UK cohort study. PLoS Med 2021; 18 (07) e1003704
  • 49 Courtine M, Bourredjem A, Gouteron A. et al. Functional recovery after total hip/knee replacement in obese people: a systematic review. Ann Phys Rehabil Med 2023; 66 (01) 101710
  • 50 Baghbani-Naghadehi F, Armijo-Olivo S, Prado CM, Gramlich L, Woodhouse LJ. Does obesity affect patient-reported outcomes following total knee arthroplasty?. BMC Musculoskelet Disord 2022; 23 (01) 55
  • 51 Roth A, Anis HK, Emara AK. et al; Cleveland Clinic OME Arthroplasty Group. The potential effects of imposing a body mass index threshold on patient-reported outcomes after total knee arthroplasty. J Arthroplasty 2021; 36 (7S): S198-S208
  • 52 Bonnefoy-Mazure A, Martz P, Armand S. et al. Influence of body mass index on sagittal knee range of motion and gait speed recovery 1-year after total knee arthroplasty. J Arthroplasty 2017; 32 (08) 2404-2410
  • 53 Napier RJ, O'Brien S, Bennett D. et al. Intra-operative and short term outcome of total knee arthroplasty in morbidly obese patients. Knee 2014; 21 (03) 784-788
  • 54 Mishra AK, Vaish A, Vaishya R. Effect of body mass index on the outcomes of primary total knee arthroplasty up to one year—a prospective study. J Clin Orthop Trauma 2022; 27: 101829
  • 55 Dubin JA, Westrich GH. A matched cohort study between cementless TKA and cemented TKA shows a reduction in tourniquet time and manipulation rate. J Orthop 2020; 21: 532-536
  • 56 Jouflas AC, Nadar AC, Royster BW. et al. Cementless metal-backed patellar components in primary total knee arthroplasty: an average 10-year follow-up. J Arthroplasty 2023; 38 (6S): S137-S144
  • 57 Kamath AF, Horneff JG, Gaffney V, Israelite CL, Nelson CL. Ethnic and gender differences in the functional disparities after primary total knee arthroplasty. Clin Orthop Relat Res 2010; 468 (12) 3355-3361
  • 58 Piuzzi NS. Cleveland Clinic O. M. E. Arthroplasty Group. Patient-reported outcomes at 1 and 2 years after total hip and knee arthroplasty: what is the minimum required follow-up?. Arch Orthop Trauma Surg 2022; 142 (09) 2121-2129
  • 59 McGlothlin AE, Lewis RJ. Minimal clinically important difference: defining what really matters to patients. JAMA 2014; 312 (13) 1342-1343