Abstract
α,β-Unsaturated carbonyl compounds are versatile building blocks in modern organic synthetic chemistry. In recent decades, various approaches have been established to access to these products, such as halogenation–dehydrohalogenation methods, organosulfur methods, organoselenium methods, earth-abundant-metal-catalyzed methods, precious-metal-catalyzed methods, and metal-free methods, etc. Among these, earth-abundant-metal-catalyzed methods (i.e., iron, cobalt, nickel, copper) continue to attract the attention of chemists because they are readily available, inexpensive, and environmentally friendly. Presently, there are only a few reviews covering earth-abundant-metal-catalyzed α,β-dehydrogenations. Hence, the aim of this short review is to provide a detailed update on the recent developments on earth-abundant-metal-catalyzed α,β-dehydrogenations of carbonyl compounds.
1 Introduction
2 Iron-Catalyzed Dehydrogenation
3 Cobalt-Catalyzed Dehydrogenation
4 Nickel-Catalyzed Dehydrogenation
5 Copper-Catalyzed Dehydrogenation
6 Conclusion
Key words
carbonyl compounds - earth-abundant metal - catalysis - α,β-dehydrogenation - α,β-unsaturated carbonyl compounds
