Subscribe to RSS
DOI: 10.1055/a-2237-8775
18F-FDG PET/CT images of adult pulmonary blastoma: a case report
A 67-year-old man was revealed a right upper lung nodule by accident during a chest CT examination 6 years ago, without any symptoms. The patient did not pay more attention to the pulmonary nodule and received no further treatment. Three years later, the patient presented with chest pain. A Chest contrast-enhanced CT showed a lobulated mass in the upper lobe of the right lung, with mild heterogeneous enhancement, and the upper edge of the mass locally invaded adjacent pleura. The patient underwent CT-guided needle biopsy, histopathological and immunohistochemical findings were consistent with diagnosis of pulmonary blastoma. Supplementary IHC of PD-L1(22C3) and PD-L1(E1L3N) were negative. In this case, we present the images of 18F-FDG PET/CT about a rare thoracic malignancy, pulmonary blastoma in adulthood, before and after chemotherapy and immunotherapy, which has never been reported before.
Publication History
Received: 15 October 2023
Accepted: 28 December 2023
Article published online:
07 February 2024
© 2024. Thieme. All rights reserved.
Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany
-
References
- 1 Luo Z, Cao C, Xu N. et al. Classic biphasic pulmonary blastoma: a case report and review of the literature. Journal of International Medical Research 2020; 48: 1-10 DOI: 10.1111/crj.13701. (PMID: 37772674)
- 2 Budzik MP, Panek G, Bińkowska M. et al. Pulmonary blastoma in a pregnant woman: a case report and brief review of the literature. BMC Pulmonary Medicine 2022; 22: 8 DOI: 10.1186/s12890-021-01804-z. (PMID: 34983474)
- 3 Travis WD, Brambilla E, Nicholson AG. et al. The 2015 World Health Organization Classification of Lung Tumors. Journal of Thoracic Oncology 2015; 10: 1243-1260 DOI: 10.1097/JTO.0000000000000630. (PMID: 26291008)
- 4 Travis WD, Brambilla E, Burke AP. et al. Introduction to The 2015 World Health Organization Classification of Tumors of the Lung, Pleura, Thymus, and Heart. Journal of Thoracic Oncology 2015; 10: 1240-1242 DOI: 10.1097/JTO.0000000000000663. (PMID: 26291007)
- 5 Sharma A, O’gorman K, Aman C. et al. A rare occurrence of bi-phasic pulmonary blastoma in an elderly male. Anticancer Research 2013; 33: 3911-3916
- 6 Yao H, Jiang X, Zeng Y. et al. Classic biphasic pulmonary blastoma: A case report and review of the literature from 2000 to 2022. The Clinical Respiratory Journal 2023; DOI: 10.1111/crj.13701:1-14.
- 7 Liman ST, Altinok T, Topcu S. et al. Survival of biphasic pulmonary blastoma. Respiratory medicine 2006; 100: 1174-1179 DOI: 10.1016/j.rmed.2005.10.026. (PMID: 16332433)
- 8 Koss MN, Hochholzer L. Pulmonary blastomas. Cancer 1991; 67: 2368-2381 DOI: 10.1002/1097-0142(19910501)67:93.0.co;2-g. (PMID: 1849449)
- 9 Tsamis I, Chachali SP, Gomatou G. et al. Pulmonary Blastoma: A Comprehensive Overview of A Rare Entity. Advances in Respiratory Medicine 2021; 89: 511-519 DOI: 10.5603/ARM.a2021.0085. (PMID: 34725809)
- 10 Brodowska-Kania D, Kotwica E, Paturej A. et al. What do we know about pulmonary blastoma?: review of literature and clinical case report. Nagoya Journal of Medical Science 2016; 78: 507-516
- 11 Sonoda LI, Wagner T, Sanghera B. et al. 18F-FDG PET_CT appearances of adult pulmonary blastoma. Clinical nuclear medicine 2013; 38: 737-738 DOI: 10.1097/RLU.0b013e3182995e2d. (PMID: 23751833)
- 12 Keu KV, Berry GJ, Quon A. Classic biphasic pulmonary blastoma demonstrated by 18F-FDG PET-CT. Clinical nuclear medicine 2014; 39: 346-348 DOI: 10.1097/RLU.0b013e31828e987c. (PMID: 23989445)
- 13 Jain TK, Singh H, Kumar R. et al. Real Time F-18 FDG PET-CT-Guided Metabolic Biopsy Targeting Differential FDG Avidity in a Pulmonary Blastoma. Nuclear Medicine and Molecular Imaging 2020; 54: 261-263 DOI: 10.1007/s13139-020-00655-6. (PMID: 33088357)
- 14 Kolekar S, Gudmundsdottir K, Olsen KE. et al. Adult pulmonary blastoma in an adult with urothelial cancer: A case report. Respiratory Medicine Case Reports 2021; 34: 101556