Steigende Überlebensraten nach Krebsdiagnosen sowie die aktuelle demographische Alterung führen zu einer wachsenden Anzahl von Langzeitüberlebenden, die oft mit Langzeit- und Spätfolgen der onkologischen Therapien kämpfen. Dieser Artikel beleuchtet die häufigsten Folgen verschiedener traditioneller Behandlungsmethoden aber auch erste Ergebnisse innovativer Therapien und zeigt, wie diese das Leben der Betroffenen beeinflussen.
Abstract
Cancer treatments, although life prolonging, are associated with side effects. The occurrence, duration, and severity of side effects vary, depending on treatment received. Long-term effects refer to effects that manifest during treatment and persist long after treatment has ended. Late effects are complications that occur after treatment has ended. These effects can have a negative impact on the functioning and quality of life of persons living with and beyond cancer. This overview aims to provide a non-exhaustive overview of the long-term and late effects associated with the traditional mainstay of cancer treatments (surgery, radiotherapy, chemotherapy) and newer treatments such as immunotherapy. In conclusion, long-term and late effects of cancer treatment can be associated with a high burden for those affected, including a reduction in their ability to function and health-related quality of life. Given the large and further growing number of cancer survivors and the abundance of long-term and late effects, it is essential to develop and implement risk-adapted, multidisciplinary survivorship care programmes.
Schlüsselwörter
Spätfolgen - Langzeitfolgen - Nebenwirkungen - Toxizität - Krebsbehandlung - Cancer Survivorship
Keywords
late effects - long-term effects - side effects - toxicity - cancer treatment - cancer survivorship
