Abstract
Background Cerebral damage after aneurysmal subarachnoid hemorrhage (SAH) results from various,
sometimes unrelated causes. After the initial hemorrhage trauma with an increase in
intracranial pressure, induced vasoconstriction, but also microcirculatory disturbances,
inflammation and pathological electrophysiological processes (cortical spreading depolarization)
can occur in the course of the disease, resulting in delayed cerebral ischemia (DCI).
In the neuroradiological context, cerebral vasospasm (CVS) remains the focus of diagnostic
imaging and endovascular therapy as a frequent component of the genesis of DCI.
Methods The amount of blood leaked during aneurysm rupture (which can be detected by CT,
for example) correlates with the occurrence and severity of CVS. CT perfusion is then
an important component in determining the indication for endovascular spasm therapies
(EST). These include intra-arterial drug administration (also as long-term microcatheter
treatment) and mechanical procedures (balloon angioplasty, vasodilatation using other
instruments such as stent retrievers, stenting).
Conclusion This review summarizes the current findings on the diagnosis and treatment of CVS
after aneurysmal SAH from a neuroradiological perspective, taking into account the
complex and up-to-date international literature.
Key Points
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Vasospasm is a frequent component of the multifactorial genesis of delayed cerebral
ischemia after SAH and remains the focus of diagnosis and treatment in the neuroradiological
context.
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The initial extent of SAH on CT is associated with the occurrence and severity of
vasospasm.
-
CT perfusion is an important component in determining the indication for endovascular
spasm therapy.
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Endovascular spasm therapies include local administration of medication (also as long-term
therapies with microcatheters) and mechanical procedures (balloon angioplasty, dilatation
using other devices such as stent retreivers, stenting).
Citation Format
Keywords
subarachnoid hemorrhage - delayed cerebral ischemia - cerebral vasospasm - endovascular
rescue treatment - nimodipine - balloon angioplasty
