Anti-Yo antibody-associated Autoimmune Encephalitis due to Breast Adenocarcinoma in a male patient

Abstract

Paraneoplastic neurological syndromes occur due to immune-mediated neuronal dysfunction secondary to systemic malignancy, and symptoms can usually be seen before malignancy. There are many subtypes that depend on the antibodies present or the proteins they target. Accurate epidemiological data are lacking as it is difficult to diagnose. We would like to present a case of anti-Yo antibody-associated encephalitis due to breast cancer in a 47-year-old male patient. When we searched the literature, we did not find a case of anti-Yo-associated autoimmune encephalitis due to breast adenocarcinoma in a male patient. For this reason, we find it worth presenting our case.

Zusammenfassung

Paraneoplastische neurologische Syndrome entstehen aufgrund einer immunvermittelten neuronalen Dysfunktion als Folge einer systemischen Malignität, und die Symptome können in der Regel vor der Malignität beobachtet werden. Es gibt viele Subtypen, die von den vorhandenen Antikörpern oder den Proteinen, auf die sie abzielen, abhängen. Genaue epidemiologische Daten fehlen, da die Diagnose schwierig ist. Wir wollten einen Fall einer Anti-Yo-Antikörper-assoziierten Enzephalitis aufgrund von Brustkrebs bei einem 47-jährigen männlichen Patienten vorstellen. Als wir die Literatur durchsuchten, fanden wir keinen Fall einer Anti-Yo-assoziierten Autoimmunenzephalitis aufgrund eines Adenokarzinoms der Brust bei einem männlichen Patienten. Aus diesem Grund hielten wir es für lohnenswert, unseren Fall vorzustellen.

Keywords

breast cancer - IVIG - encephalitis - paraneoplastic

Schlüsselwörter

Brustkrebs - IVIG - Enzephalitis - paraneoplastisch

Publication History

Received: 20 November 2022

Accepted after revision: 07 April 2024

Article published online:
12 June 2024

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