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Synthesis
DOI: 10.1055/a-2349-6836
DOI: 10.1055/a-2349-6836
paper
Special Topic Dedicated to Prof. H. Ila
Iron(III)-Catalysed Povarov Cyclisation for the Synthesis of Fused Dibenzo[b,f][1,7]naphthyridine Embedded Arylpyrrolo Scaffolds
This work was financially supported by research funds from Jadavpur University and the University Grants Commission.
Abstract
An FeCl3-catalyzed Povarov reaction for the efficient synthesis of dibenzo[b,f][1,7]naphthyridines utilizing 1-(2-alkynylaryl)-2-pyrrolecarbaldehydes and arylamines in excellent yields is demonstrated. The essential features of the present strategy are easy preparation of substrates, broad substrate scope, mild reaction conditions, and high atom economy and yields, in the presence of environmentally friendly iron catalysis.
Key words
arylpyrrolecarbaldehydes - phosphorus oxychloride - arylamines - 1,7-naphthyridines - ferric chlorideSupporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/a-2349-6836.
- Supporting Information
Publication History
Received: 11 May 2024
Accepted after revision: 20 June 2024
Accepted Manuscript online:
20 June 2024
Article published online:
15 July 2024
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For recent review articles on iron catalysis, see: