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J Neurol Surg B Skull Base
DOI: 10.1055/a-2358-9228
Original Article

“Just got diagnosed; what worked for you?”: A Mixed-Methods Analysis of Treatment Experiences in the Prolactinoma Subreddit

Rose Dimitroyannis
1   University of Chicago Pritzker School of Medicine, Chicago, United States (Ringgold ID: RIN12246)
,
David Fenton
2   University of Chicago Pritzker School of Medicine, Chicago, United States (Ringgold ID: RIN12246)
,
Sharanya Thodupunoori
3   University of Chicago Pritzker School of Medicine, Chicago, United States (Ringgold ID: RIN12246)
,
Stella Cho
4   University of Chicago Pritzker School of Medicine, Chicago, United States (Ringgold ID: RIN12246)
,
Rachel Nordgren
5   Department of Public Health Sciences, University of Chicago Division of the Biological Sciences, Chicago, United States (Ringgold ID: RIN123964)
,
Sean Polster
6   Neurological Surgery, The University of Chicago Medicine, Chicago, United States (Ringgold ID: RIN21727)
,
Peleg Horowitz
7   Department of Neurological Surgery, The University of Chicago Medicine, Chicago, United States (Ringgold ID: RIN21727)
,
Paramita Das
6   Neurological Surgery, The University of Chicago Medicine, Chicago, United States (Ringgold ID: RIN21727)
,
Christopher Roxbury
8   Otolaryngology - Head & Neck Surgery, The University of Chicago Medicine, Chicago, United States (Ringgold ID: RIN21727)
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ABSTRACT INTRODUCTION With improvement in complication and remission rates, recent studies have suggested the viability of transsphenoidal surgery as first-line management for prolactinomas. Reddit, an online forum, allows posters to interact with one another, discuss symptoms, treatments, and disease courses through specialized forums known as “subreddits”. Given the lack of research comparing patient experience on pharmacotherapy versus surgery, we sought to assess the sentiment of treatment within the “r/Prolactinoma subreddit” community. METHODS A search was done by filtering the r/Prolactinoma subreddit. Posts were sorted by “top” of “all time,” meaning entries with the most engagement throughout the site's history. Welch’s t-test was used to analyze treatment type, while sentiment regarding treatment was analyzed using grounded theory qualitative methods. RESULTS From 189 total entries, 82 were included; 33% (n=27/82) were posts. Of posters disclosing their treatment, 11% underwent surgery (n=9/79), while 76% received medication (n=60/79). The proportion of positive: negative sentiment and level of engagement on posts regarding pharmacotherapy vs surgical treatments were not significantly different (p>0.05). Qualitative analysis showed themes of changes after medical treatment, immediate changes post-surgery, and online community. CONCLUSION Our mixed-methods study found statistically non-significant differences in sentiment when comparing Reddit posts from patients who underwent medical and surgical management. Qualitative analysis revealed several themes regarding patients’ perceptions of medical and surgical management and the benefits of an online community. The qualitative themes brought to light by this study may serve to inform future studies examining the patient experience with prolactinoma care.



Publication History

Received: 19 March 2024

Accepted: 29 June 2024

Accepted Manuscript online:
02 July 2024

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