Ni–H-Catalyzed Chemo- and Regioselective Hydroarylation of Vinylsilanes

Abstract

A chemo- and regioselective hydroarylation of vinylsilanes with (hetero)aryl iodides under Ni–H catalysis is reported. This mild and straightforward protocol furnishes the anti-Markovnikov products in good yields as single regioisomers. This study demonstrates excellent control over the chemoselectivity and complements existing methods for the construction of homobenzylic silanes.

Key words

cross-coupling - hydroarylation - nickel - regioselectivity - silicon

Publication History

Received: 21 June 2024

Accepted after revision: 16 July 2024

Accepted Manuscript online:
16 July 2024

Article published online:
06 August 2024

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