Synthesis 2024; 56(22): 3512-3518
DOI: 10.1055/a-2378-4540
paper

Solvent-Controlled Divergent Synthesis of Thiocyanated Carbazoles and Di/Triphenylamines

You-Hui Tang
a   Key Laboratory of Advanced Mass Spectrometry and Molecular Analysis of Zhejiang Province, Institute of Mass Spectrometry, School of Material Science and Chemical Engineering, Ningbo University, Ningbo, Zhejiang 315211, P. R. of China
,
Peng Chen
a   Key Laboratory of Advanced Mass Spectrometry and Molecular Analysis of Zhejiang Province, Institute of Mass Spectrometry, School of Material Science and Chemical Engineering, Ningbo University, Ningbo, Zhejiang 315211, P. R. of China
,
Jin Yin
a   Key Laboratory of Advanced Mass Spectrometry and Molecular Analysis of Zhejiang Province, Institute of Mass Spectrometry, School of Material Science and Chemical Engineering, Ningbo University, Ningbo, Zhejiang 315211, P. R. of China
,
Jianghuan Shi
b   Ningbo Institute of Measurement and Testing (Ningbo Inspection and Testing Center for New Materials), Ningbo 315048, P. R. of China
,
Yi-Jun Jiang
a   Key Laboratory of Advanced Mass Spectrometry and Molecular Analysis of Zhejiang Province, Institute of Mass Spectrometry, School of Material Science and Chemical Engineering, Ningbo University, Ningbo, Zhejiang 315211, P. R. of China
› Author Affiliations
This research was supported by Zhejiang Provincial Natural Science Foundation of China (Grant No. LY23B040001) and Programs Supported­ by Ningbo Natural Science Foundation (Grant No. 202003N4009).


Abstract

A solvent-controlled divergent thiocyanation of carbazoles and di/triphenylamines has been developed. Using either CH3CN/H2O (3:1) or DMSO as the solvent, a facile and efficient protocol for the solvent-controlled divergent synthesis of mono- and di-thiocyanation of carbazoles and di/triphenylamines was achieved. The salient features of this transformation include simple and mild reaction conditions, easily available substrates, and broad substrate scope.

Supporting Information



Publication History

Received: 30 June 2024

Accepted after revision: 01 August 2024

Accepted Manuscript online:
01 August 2024

Article published online:
26 August 2024

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