J Neurol Surg A Cent Eur Neurosurg
DOI: 10.1055/a-2418-7705
Original Article

Early-Onset Adjacent Vertebral Fractures after Balloon Kyphoplasty and SpineJack Kyphoplasty for the Management of Single-Level Thoracolumbar Vertebral Compression Fractures

Ming-Hsuan Chung
1   Department of Neurological Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Republic of China
,
Yun-Ju Yang
1   Department of Neurological Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Republic of China
,
Yi-Chieh Wu
1   Department of Neurological Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Republic of China
,
Guann-Juh Chen
1   Department of Neurological Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Republic of China
,
Da-Tong Ju
1   Department of Neurological Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Republic of China
,
Kuan-Nien Chou
1   Department of Neurological Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Republic of China
› Author Affiliations
Funding None.

Abstract

Background The aim of this study was to evaluate the risk factors contributing to early-onset adjacent level fractures (ALFs) occurring within 1 month following either balloon kyphoplasty (BKP) or SpineJack kyphoplasty (SJ) for the treatment of thoracolumbar vertebral compression fractures (TLVCFs).

Methods This retrospective analysis enrolled patients with single-level TLVCFs (T11–L2) who underwent either BKP or SJ between July 2013 and June 2019. We recorded the ALF occurrences within 1 month. Age, osteoporosis, severity and shape of TLVCFs, and surgical type were compared between patients with and without early-onset ALFs.

Results Altogether, 106 TLVCF patients were enrolled, comprising 64 BKP and 42 SJ cases. We observed 19 early-onset ALFs, with 9 and 10 cases in the BKP and SJ, respectively. Patients with early-onset ALFs have significantly more severe TLCVFs (severe vs. mild, 25 vs. 0%, p = 0.055), and wedge-shaped TLVCFs (26.47 vs. 2.63%, p = 0.002), older age (81.05 vs. 73.34 years, p < 0.001), and kyphoplasty performed within 1 month are risk factors for early-onset ALFs (26.92 vs. 9.26%, p = 0.018). Univariable analysis showed that kyphoplasty timing within 1 month (odds ratio [OR]: 0.193; p = 0.008), wedge-shaped TLVCFs (OR: 5.358; p = 0.036), and advanced age (OR: 1.119; p = 0.001) are significant risk factors for early-onset ALFs.

Conclusions The occurrence rate of early-onset ALFs between BKP or SJ techniques in treating TLVCFs does not differ. Preoperative wedge-shaped TLVCFs, advanced age, and early treatment within 1 month are the risk factors for early-onset ALFs following kyphoplasty for TLVCFs.

Authors' Contributions

K.-N.C. conceived the presented idea and supervised the findings of this work. M.H.C. collected and analyzed the data. M.H.C. and Y.-C.W. prepared the manuscript, including figures and tables. Y.-J.Y. assisted with the image assessment. All the authors approved the final manuscript.




Publication History

Received: 23 June 2024

Accepted: 17 September 2024

Accepted Manuscript online:
19 September 2024

Article published online:
06 December 2024

© 2024. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 
  • References

  • 1 Ballane G, Cauley JA, Luckey MM, El-Hajj Fuleihan G. Worldwide prevalence and incidence of osteoporotic vertebral fractures. Osteoporos Int 2017; 28 (05) 1531-1542
  • 2 Trout AT, Kallmes DF, Kaufmann TJ. New fractures after vertebroplasty: adjacent fractures occur significantly sooner. AJNR Am J Neuroradiol 2006; 27 (01) 217-223
  • 3 Jang HD, Kim EH, Lee JC. et al. Management of osteoporotic vertebral fracture: review update 2022. Asian Spine J 2022; 16 (06) 934-946
  • 4 Cankaya D, Yilmaz S, Deveci A. et al. Clinical and radiological outcomes of conservative treatment after stable post-traumatic thoracolumbar fractures in elderly: is it really best option for all elderly patients?. Ann Med Surg (Lond) 2015; 4 (04) 346-350
  • 5 De Negri P, Tirri T, Paternoster G, Modano P. Treatment of painful osteoporotic or traumatic vertebral compression fractures by percutaneous vertebral augmentation procedures: a nonrandomized comparison between vertebroplasty and kyphoplasty. Clin J Pain 2007; 23 (05) 425-430
  • 6 Hu KZ, Chen SC, Xu L. Comparison of percutaneous balloon dilation kyphoplasty and percutaneous vertebroplasty in treatment for thoracolumbar vertebral compression fractures. Eur Rev Med Pharmacol Sci 2018; 22 (1, Suppl): 96-102
  • 7 Wang B, Zhao CP, Song LX, Zhu L. Balloon kyphoplasty versus percutaneous vertebroplasty for osteoporotic vertebral compression fracture: a meta-analysis and systematic review. J Orthop Surg Res 2018; 13 (01) 264
  • 8 Daher M, Kreichati G, Kharrat K, Sebaaly A. Vertebroplasty versus kyphoplasty in the treatment of osteoporotic vertebral compression fractures: a meta-analysis. World Neurosurg 2023; 171: 65-71
  • 9 Filippiadis DK, Marcia S, Ryan A. et al. New Implant-Based Technologies in the Spine. Cardiovasc Intervent Radiol 2018; 41 (10) 1463-1473
  • 10 Noriega D, Marcia S, Theumann N. et al. A prospective, international, randomized, noninferiority study comparing an implantable titanium vertebral augmentation device versus balloon kyphoplasty in the reduction of vertebral compression fractures (SAKOS study). Spine J 2019; 19 (11) 1782-1795
  • 11 Noriega DC, Rodrίguez-Monsalve F, Ramajo R, Sánchez-Lite I, Toribio B, Ardura F. Long-term safety and clinical performance of kyphoplasty and SpineJack® procedures in the treatment of osteoporotic vertebral compression fractures: a pilot, monocentric, investigator-initiated study. Osteoporos Int 2019; 30 (03) 637-645
  • 12 Fribourg D, Tang C, Sra P, Delamarter R, Bae H. Incidence of subsequent vertebral fracture after kyphoplasty. Spine 2004; 29 (20) 2270-2276 , discussion 2277
  • 13 Wilcox RK. The biomechanical effect of vertebroplasty on the adjacent vertebral body: a finite element study. Proc Inst Mech Eng H 2006; 220 (04) 565-572
  • 14 Alamin T, Kleimeyer JP, Woodall JR, Agarwal V, Don A, Lindsey D. Improved biomechanics of two alternative kyphoplasty cementation methods limit vertebral recollapse. J Orthop Res 2018; 36 (12) 3225-3230
  • 15 Genant HK, Wu CY, van Kuijk C, Nevitt MC. Vertebral fracture assessment using a semiquantitative technique. J Bone Miner Res 1993; 8 (09) 1137-1148
  • 16 Guglielmi G, Diacinti D, van Kuijk C. et al. Vertebral morphometry: current methods and recent advances. Eur Radiol 2008; 18 (07) 1484-1496
  • 17 Marcia S, Muto M, Hirsch JA. et al. What is the role of vertebral augmentation for osteoporotic fractures? A review of the recent literature. Neuroradiology 2018; 60 (08) 777-783
  • 18 Beall D, Lorio MP, Yun BM, Runa MJ, Ong KL, Warner CB. Review of vertebral augmentation: an updated meta-analysis of the effectiveness. Int J Spine Surg 2018; 12 (03) 295-321
  • 19 Yi X, Lu H, Tian F. et al. Recompression in new levels after percutaneous vertebroplasty and kyphoplasty compared with conservative treatment. Arch Orthop Trauma Surg 2014; 134 (01) 21-30
  • 20 Li HM, Zhang RJ, Gao H. et al. New vertebral fractures after osteoporotic vertebral compression fracture between balloon kyphoplasty and nonsurgical treatment PRISMA. Medicine (Baltimore) 2018; 97 (40) e12666
  • 21 Morozumi M, Matsubara Y, Muramoto A. et al. A study of risk factors for early-onset adjacent vertebral fractures after kyphoplasty. Global Spine J 2020; 10 (01) 13-20
  • 22 Zhang T, Wang Y, Zhang P, Xue F, Zhang D, Jiang B. What are the risk factors for adjacent vertebral fracture after vertebral augmentation? A meta-analysis of published studies. Global Spine J 2022; 12 (01) 130-141
  • 23 Fahim DK, Sun K, Tawackoli W. et al. Premature adjacent vertebral fracture after vertebroplasty: a biomechanical study. Neurosurgery 2011; 69 (03) 733-744
  • 24 Berlemann U, Ferguson SJ, Nolte LP, Heini PF. Adjacent vertebral failure after vertebroplasty. A biomechanical investigation. J Bone Joint Surg Br 2002; 84 (05) 748-752
  • 25 Papanastassiou ID, Filis A, Aghayev K, Kokkalis ZT, Gerochristou MA, Vrionis FD. Adverse prognostic factors and optimal intervention time for kyphoplasty/vertebroplasty in osteoporotic fractures. BioMed Res Int 2014; 2014: 925683
  • 26 Minamide A, Maeda T, Yamada H. et al. Early versus delayed kyphoplasty for thoracolumbar osteoporotic vertebral fractures: the effect of timing on clinical and radiographic outcomes and subsequent compression fractures. Clin Neurol Neurosurg 2018; 173: 176-181
  • 27 Zhou X, Meng X, Zhu H, Zhu Y, Yuan W. Early versus late percutaneous kyphoplasty for treating osteoporotic vertebral compression fracture: a retrospective study. Clin Neurol Neurosurg 2019; 180: 101-105
  • 28 Yang CC, Chien JT, Tsai TY, Yeh KT, Lee RP, Wu WT. Earlier vertebroplasty for osteoporotic thoracolumbar compression fracture may minimize the subsequent development of adjacent fractures: a retrospective study. Pain Physician 2018; 21 (05) E483-E491
  • 29 Zuo XH, Chen YB, Xie P. et al. Finite element analysis of wedge and biconcave deformity in four different height restoration after augmentation of osteoporotic vertebral compression fractures. J Orthop Surg Res 2021; 16 (01) 138
  • 30 Jhong GH, Chung YH, Li CT, Chen YN, Chang CW, Chang CH. Numerical comparison of restored vertebral body height after incomplete burst fracture of the lumbar spine. J Pers Med 2022; 12 (02) 253