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DOI: 10.1055/a-2479-0995
Achieving Sustainability in Assembly of Modified Nucleosides Using Green Solvents
Supported by: Rasayan Inc. E279924
Chemical modifications of nucleosides has been a topic of special interest for researchers given the plethora of applications these structural motifs have been able to demonstrate. For decades, such modifications have been performed in conventional volatile organic solvents that have severe environmental implications. Recent trend suggests a shift in the strategy with many researchers using sustainable and green solvents such as ionic liquids (ILs), H2O, Deep Eutectic Solvents (DES) and 2-MeTHF for performing key transformations on the nucleoside structural motif. This review critically analyzes examples of nucleoside functionalization carried out in different sustainable solvents and also helps to assess the feasibility of such solvent choices for further applications.
Publication History
Received: 21 September 2024
Accepted after revision: 18 November 2024
Accepted Manuscript online:
19 November 2024
© . The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/).
Georg Thieme Verlag KG
Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany
Mahadev V Kudalkar, Manisha Patel, Yogesh S Sanghvi, Anant Kapdi. Achieving Sustainability in Assembly of Modified Nucleosides Using Green Solvents. Sustainability & Circularity NOW ; 0: a24790995.
DOI: 10.1055/a-2479-0995