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DOI: 10.1055/a-2515-3240
Mental Health After Childbirth in Women with Previous Bariatric Surgery: The SPOtMom Pilot Study
Registration number (trial ID): NCT04297956, Trial registry: ClinicalTrials.gov (http://www.clinicaltrials.gov/), Type of Study: prospective survey, conducted at two centers
Abstract
Introduction
Currently, no data are available using standardized instruments for evaluating the postpartum mental health of women with previous bariatric surgery. The aim of this pilot study was to assess postpartum mental health in women following bariatric surgery and to establish appropriate tools for a prospective registry study in the future.
Methods
In this survey, the mental health of 22 women during the first weeks postpartum was examined (T1) and their status at least 6 months after childbirth was prospectively assessed (T2). Symptoms of depression and anxiety were evaluated with standardized questionnaires and depression was diagnosed with structured diagnostic interviews (SCID-5).
Results
At T1, 3/22 women (14%) reported depressive or anxiety symptoms, and in these women, the diagnosis of depression was established. In comparison with T1, at T2, symptomatology for depression or anxiety increased to 32% and 27% of patients, respectively, but only one woman was diagnosed with depression. In comparison to patients without symptoms, patients with signs of depression or anxiety or both had lower total body weight loss and, more often, a personal or family history of depressive disorders.
Conclusion
Our pilot study suggests that the rate of postpartum depression in women after BS might be higher than in the general population. High symptom levels of depression and anxiety emphasize the necessity of long-term bariatric follow-up care. Further research is needed to evaluate if prevalence of depression or anxiety disorder or both is higher in this patient group as compared to other patients after bariatric surgery.
Publication History
Received: 30 May 2024
Accepted after revision: 02 December 2024
Article published online:
12 March 2025
© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).
Georg Thieme Verlag KG
Oswald-Hesse-Straße 50, 70469 Stuttgart, Germany
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References
- 1 Dawes AJ, Maggard-Gibbons M, Maher AR. et al. Mental health conditions among patients seeking and undergoing bariatric surgery: A meta-analysis. JAMA 2016; 315: 150-163
- 2 Gill H, Kang S, Lee Y. et al. The long-term effect of bariatric surgery on depression and anxiety. J Affect Disord 2019; 246: 886-894
- 3 Spirou D, Raman J, Smith E. Psychological outcomes following surgical and endoscopic bariatric procedures: A systematic review. Obes Rev 2020; 21: e12998
- 4 Maggard MA, Yermilov I, Li Z. et al. Pregnancy and fertility following bariatric surgery: A systematic review. JAMA 2008; 300: 2286-2296
- 5 Milone M, De Placido G, Musella M. et al. Incidence of successful pregnancy after weight loss interventions in infertile women: A systematic review and meta-analysis of the literature. Obes Surg 2016; 26: 443-451
- 6 Stewart DE, Vigod SN. Postpartum depression: Pathophysiology, treatment, and emerging therapeutics. Annu Rev Med 2019; 70: 183-196
- 7 Dennis CL, Falah-Hassani K, Shiri R. Prevalence of antenatal and postnatal anxiety: Systematic review and meta-analysis. Br J Psychiatry 2017; 210: 315-323
- 8 Dachew BA, Ayano G, Betts K. et al. The impact of pre-pregnancy BMI on maternal depressive and anxiety symptoms during pregnancy and the postpartum period: A systematic review and meta-analysis. J Affect Disord 2021; 281: 321-330
- 9 Jans G, Matthys C, Bogaerts A. et al. Depression and anxiety: Lack of associations with an inadequate diet in a sample of pregnant women with a history of bariatric surgery-a multicenter prospective controlled cohort study. Obes Surg 2018; 28: 1629-1635
- 10 Walter LB, Dolzan D, Areias T. et al. Adverse neonatal and obstetric outcomes in a 20-year Brazilian retrospective cohort of pregnancies after bariatric surgery. Obes Surg 2021; 31: 2859-2868
- 11 da Rocha ACN, da Cunha ACB, da Silva JF. Prevalence of depression in pregnant women with bariatric surgery history and associated factors. Rev Bras Ginecol Obstet 2022; 44: 109-117
- 12 Kim J, Kelley J, Davidson L. et al. Depression and anxiety incidence during pregnancy between bariatric surgery patients and matched control subjects. Obes Surg 2022; 32: 1962-1968
- 13 Yu Y, Ma Q, Hollenbach S. et al. Pregnant women following bariatric surgery: A focus on Maternal Mental Health and Its Impact on Birth Outcomes. Obes Surg 2022; 32: 3696-3704
- 14 Kroenke K, Spitzer RL, Williams JB. The PHQ-9: Validity of a brief depression severity measure. J Gen Intern Med 2001; 16: 606-613
- 15 Cox JL, Holden JM, Sagovsky R. Detection of postnatal depression. Development of the 10-item Edinburgh Postnatal Depression Scale. Br J Psychiatry 1987; 150: 782-786
- 16 Wang YP, Gorenstein C. Psychometric properties of the Beck Depression Inventory-II: A comprehensive review. Braz J Psychiatry 2013; 35: 416-431
- 17 Spitzer RL, Kroenke K, Williams JB. et al. A brief measure for assessing generalized anxiety disorder: The GAD-7. Arch Intern Med 2006; 166: 1092-1097
- 18 Levis B, Benedetti A, Thombs BD. Accuracy of Patient Health Questionnaire-9 (PHQ-9) for screening to detect major depression: Individual participant data meta-analysis. BMJ 2019; 365: l1476
- 19 von Glischinski M, von Brachel R, Hirschfeld G. How depressed is "depressed"? A systematic review and diagnostic meta-analysis of optimal cut points for the Beck Depression Inventory revised (BDI-II). Qual Life Res 2019; 28: 1111-1118
- 20 Osório FL, Loureiro SR, Hallak JEC. et al. Clinical validity and intrarater and test-retest reliability of the Structured Clinical Interview for DSM-5 – Clinician Version (SCID-5-CV). Psychiatry Clin Neurosci 2019; 73: 754-760
- 21 Law S, Dong S, Zhou F. et al. Bariatric surgery and mental health outcomes: An umbrella review. Front Endocrinol (Lausanne) 2023; 14: 1283621
- 22 Li JR, Cao J, Wei J. et al. Case Report: Semaglutide-associated depression: A report of two cases. Front Psychiatry 2023; 14: 1238353
- 23 Tang H, Lu Y, Donahoo WT. et al. Glucagon-like peptide-1 receptor agonists and risk for suicidal ideation and behaviors in U.S. older adults with type 2 diabetes: A target trial emulation study. Ann Intern Med 2024; 177: 1004-1015
- 24 McIntyre RS, Mansur RB, Rosenblat JD. et al. The association between glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and suicidality: Reports to the Food and Drug Administration Adverse Event Reporting System (FAERS). Expert Opin Drug Saf 2024; 23: 47-55
- 25 (WHO) WHO. Mental Health and COVID-19: Early evidence of the pandemic’s impact: Scientific brief. Available https://www.who.int/publications/i/item/WHO-2019-nCoV-Sci_Brief-Mental_health-2022.1
- 26 Takayanagi Y, Spira AP, Roth KB. et al. Accuracy of reports of lifetime mental and physical disorders: Results from the Baltimore Epidemiological Catchment Area study. JAMA Psychiatry 2014; 71: 273-280
- 27 Navarro P, García-Esteve L, Ascaso C. et al. Non-psychotic psychiatric disorders after childbirth: Prevalence and comorbidity in a community sample. J Affect Disord 2008; 109: 171-176
- 28 Reck C, Struben K, Backenstrass M. et al. Prevalence, onset and comorbidity of postpartum anxiety and depressive disorders. Acta Psychiatr Scand 2008; 118: 459-468
- 29 Gjerdingen D, Crow S, McGovern P. et al. Postpartum depression screening at well-child visits: Validity of a 2-question screen and the PHQ-9. Ann Fam Med 2009; 7: 63-70
- 30 Gjerdingen D, Crow S, McGovern P. et al. Changes in depressive symptoms over 0-9 months postpartum. J Womens Health (Larchmt) 2011; 20: 381-386
- 31 Maliszewska K, Świątkowska-Freund M, Bidzan M. et al. Screening for maternal postpartum depression and associations with personality traits and social support. A Polish follow-upstudy 4 weeks and 3 months after delivery. Psychiatr Pol 2017; 51: 889-898
- 32 Gigantesco A, Palumbo G, Cena L. et al. A brief depression screening tool for perinatal clinical practice: The performance of the PHQ-2 compared with the PHQ-9. J Midwifery Womens Health 2022; 67: 586-592
- 33 Pawar G, Wetzker C, Gjerdingen D. Prevalence of depressive symptoms in the immediate postpartum period. J Am Board Fam Med 2011; 24: 258-261
- 34 Ceulemans M, Foulon V, Ngo E. et al. Mental health status of pregnant and breastfeeding women during the COVID-19 pandemic-A multinational cross-sectional study. Acta Obstet Gynecol Scand 2021; 100: 1219-1229
- 35 Bodnar-Deren S, Klipstein K, Fersh M. et al. Suicidal ideation during the postpartum period. J Womens Health (Larchmt) 2016; 25: 1219-1224
- 36 Hayden MJ, Murphy KD, Brown WA. et al. Axis I disorders in adjustable gastric band patients: The relationship between psychopathology and weight loss. Obes Surg 2014; 24: 1469-1475
- 37 Kalarchian MA, King WC, Devlin MJ. et al. Mental disorders and weight change in a prospective study of bariatric surgery patients: 7 years of follow-up. Surg Obes Relat Dis 2019; 15: 739-748
- 38 Hilgendorf W, Butler A, Timsina L. et al. A behavioral rating system predicts weight loss and quality of life after bariatric surgery. Surg Obes Relat Dis 2018; 14: 1167-1172
- 39 Youssef A, Keown-Stoneman C, Maunder R. et al. Differences in physical and mental health-related quality of life outcomes 3 years after bariatric surgery: A group-based trajectory analysis. Surg Obes Relat Dis 2020; 16: 1837-1849
- 40 Köhler H, Dorozhkina R, Gruner-Labitzke K. et al. Specific health knowledge and health literacy of patients before and after bariatric surgery: A cross-sectional study. Obes Facts 2020; 13: 166-178
- 41 Schag K, Mack I, Giel KE. et al. The impact of impulsivity on weight loss four years after bariatric surgery. Nutrients 2016; 8: 721
- 42 Gordon EL, Terrill AL, Smith TW. et al. Overvaluation of shape and weight (not BMI) associated with depressive symptoms and binge eating symptoms pre- and post-bariatric surgery. Obes Surg 2022; 32: 2272-2279
- 43 McGarrity LA, Terrill AL, Martinez PL. et al. The role of resilience in psychological health among bariatric surgery patients. Obes Surg 2022; 32: 792-800
- 44 Busetto L, Dicker D, Azran C. et al. Practical recommendations of the obesity management task force of the European Association for the Study of Obesity for the Post-Bariatric Surgery Medical Management. Obes Facts 2017; 10: 597-632
- 45 Shawe J, Ceulemans D, Akhter Z. et al. Pregnancy after bariatric surgery: Consensus recommendations for periconception, antenatal and postnatal care. Obes Rev 2019; 20: 1507-1522
- 46 Mühlhans B, Horbach T, de Zwaan M. Psychiatric disorders in bariatric surgery candidates: A review of the literature and results of a German prebariatric surgery sample. Gen Hosp Psychiatry 2009; 31: 414-421
- 47 de Zwaan M, Enderle J, Wagner S. et al. Anxiety and depression in bariatric surgery patients: A prospective, follow-up study using structured clinical interviews. J Affect Disord 2011; 133: 61-68
- 48 Malik S, Mitchell JE, Engel S. et al. Psychopathology in bariatric surgery candidates: A review of studies using structured diagnostic interviews. Compr Psychiatry 2014; 55: 248-259
- 49 Zacher Kjeldsen MM, Bricca A, Liu X. et al. Family history of psychiatric disorders as a risk factor for maternal postpartum depression: A systematic review and meta-analysis. JAMA Psychiatry 2022; 79: 1004-1013
- 50 Hutchens BF, Kearney J. Risk factors for postpartum depression: An umbrella review. J Midwifery Womens Health 2020; 65: 96-108
- 51 El Ansari W, Elhag W. Weight regain and insufficient weight loss after bariatric surgery: Definitions, prevalence, mechanisms, predictors, prevention and management strategies, and knowledge gaps-a scoping review. Obes Surg 2021; 31: 1755-1766
- 52 Alyahya RA, Alnujaidi MA. Prevalence and outcomes of depression after bariatric surgery: A systematic review and meta-analysis. Cureus 2022; 14: e25651