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Synthesis
DOI: 10.1055/a-2518-0987
paper

EDA complexation of two donor molecules initiating radical cation cyclizations

Julian Kürschner
1   Organic chemistry, University of Münster, Münster, Germany (Ringgold ID: RIN9185)
,
Martin Utikal
1   Organic chemistry, University of Münster, Münster, Germany (Ringgold ID: RIN9185)
,
Lena Lezius
1   Organic chemistry, University of Münster, Münster, Germany (Ringgold ID: RIN9185)
,
Rubaishan Jeyaseelan
1   Organic chemistry, University of Münster, Münster, Germany (Ringgold ID: RIN9185)
,
Line Dahl Næsborg 
1   Organic chemistry, University of Münster, Münster, Germany (Ringgold ID: RIN9185)
› Author AffiliationsSupported by: Fonds der Chemischen Industrie Liebig fellowship
Supported by: Deutsche Forschungsgemeinschaft CRC 1459 - 433682494,GRK 2678-437785492
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We present a catalyst-free EDA complexation of two donor molecules using an acidic solvent. The electron-rich aromatic compound E-anethole is slowly protonated by the solvent hexafluoroisopropanol (HFIP), leading to the rapid formation of a photoactive EDA complex between a protonated E-anethole and another E-anethole molecule. This resulting EDA complex initiates radical chain cyclization reactions under green light irradiation.



Publication History

Received: 13 December 2024

Accepted after revision: 16 January 2025

Accepted Manuscript online:
16 January 2025

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