Download PDF
Zeitschrift für Komplementärmedizin 2025; 17(02): 54-59
DOI: 10.1055/a-2518-9320
Praxis
Phytotherapie bei Reizdarmsyndrom

Reizdarmsyndrom und Phytotherapie: leitlinienkonforme Behandlung im Überblick

Sandra Utz
,
Jost Langhorst
› Further Information
    Permissions and Reprints

Summary

Das Reizdarmsyndrom (RDS) ist eine häufige funktionelle Darmstörung mit vielfältigen Symptomen wie Bauchschmerzen, Blähungen und Stuhlveränderungen. Phytotherapeutika stellen eine sinnvolle Ergänzung in der RDS-Therapie dar. Auch die aktuelle S3-Leitlinie empfiehlt Phytotherapeutika zur Behandlung des RDS, vor allem lösliche Ballaststoffe wie Flohsamenschalen oder Pfefferminz- und Kümmelöl. Trotz vielversprechender Ergebnisse sind weitere qualitativ hochwertige Studien erforderlich, um die Evidenzbasis zu stärken und die Standardisierung der Präparate zu verbessern.

Keywords

Reizdarmsyndrom - Phytotherapie - S3-Leitlinien - Phytopharmaka - pflanzliche Arzneimittel


Publication History

Article published online:
14 April 2025

© 2025. Thieme. All rights reserved.

© Karl F. Haug Verlag in MVS Medizinverlage Stuttgart GmbH & Co.
KG

 

  • Literatur

  • 1 Hetterich L, Zipfel S, Stengel A.. Gastrointestinale somatoforme Störungen.. Fortschr Neurol Psych 2019; 87 (09) 512-525
    Search in Google Scholar
  • 2 Sperber AD, Bangdiwala SI, Drossman DA. et al Worldwide prevalence and burden of functional gastrointestinal disorders, results of Rome Foundation Global Study.. Gastroenterology 2021; 160 (01) 99-114
    CrossrefPubMedSearch in Google Scholar
  • 3 World Health Organization (WHO). International Statistical Classification of Diseases and Related Health Problems. 10th rev. (ICD-10); 2019. Im Internet:. https://icd.who.int/browse10/ Stand: 11.03.2025
  • 4 World Health Organization (WHO). International Classification of Diseases. 11th rev. (ICD-11); 2022. Im Internet:. https://icd.who.int/en Stand: 11.03.2025
  • 5 DGVS, DGNM AWMF. S3-Leitlinie: Definition, Pathophysiologie, Diagnostik und Therapie des Reizdarmsyndroms – Version: 2.3, AWMF-Register-Nr.: 021-016; 31.03.2021. Im Internet:. https://register.awmf.org/de/leitlinien/detail/ 021-016; Stand: 11.03.2025
  • 6 Halmos EP, Power VA, Shepherd SJ. et al A diet low in FODMAPs reduces symptoms of irritable bowel syndrome.. Gastroenterology 2014; 146 (01) 67-75
    PubMedSearch in Google Scholar
  • 7 Schumann D, Klose P, Lauche R. et al Low fermentable, oligo-, di-, mono-saccharides and polyol diet in the treatment of irritable bowel syndrome: A systematic review and meta-analysis.. Nutrition 2018; 45: 24-31
    PubMedSearch in Google Scholar
  • 8 Fritscher-Ravens A, Pflaum T, Mösinger M. et al Many patients with irritable bowel syndrome have atypical food allergies not associated with immunoglobulin E.. Gastroenterology 2019; 157 (01) 109-118
    CrossrefPubMedSearch in Google Scholar
  • 9 Langhorst J, Madisch A.. Reizdarmsyndrom: Nichtmedikamentöse Therapie.. Verdauungskrankh 2022; 40 (06) 270-276
    Search in Google Scholar
  • 10 Schnabel K, Binting S, Witt CM. et al Use of complementary and alternative medicine by older adults – A cross-sectional survey.. BMC Geriatr 2014; 14: 1-9
    CrossrefPubMedSearch in Google Scholar
  • 11 Statista. Phytopharmaka – Top 10 der umsatzstärksten Indikationsgruppen von Phytopharmaka auf dem deutschen Apothekenmarkt 2023. Im Internet:. https://de.statista.com/statistik/daten/studie/526054/umfrage/top-10-der-umsatzstaerksten-indikationsgruppen-von-phytopharmaka/ Stand: 11.03.2025
  • 12 Ford AC, Talley NJ, Spiegel BM. et al Effect of fibre, antispasmodics, and peppermint oil in the treatment of irritable bowel syndrome: Systematic review and meta-analysis.. BMF 2008; 337: a2313
    Search in Google Scholar
  • 13 Khanna R, MacDonald JK, Levesque BG.. Peppermint oil for the treatment of irritable bowel syndrome: A systematic review and meta-analysis.. J Clin Gastroenterol 2014; 48 (06) 505-512
    CrossrefPubMedSearch in Google Scholar
  • 14 Harrington AM, Hughes PA, Martin CM. et al A novel role for TRPM8 in visceral afferent function.. Pain 2011; 152 (07) 1459-1468
    CrossrefPubMedSearch in Google Scholar
  • 15 Cash BD, Epstein MS, Shah SM.. A novel delivery system of peppermint oil is an effective therapy for irritable bowel syndrome symptoms.. Digest Diseas Sci 2016; 61: 560-571
    Search in Google Scholar
  • 16 Merat S, Khalili S, Mostajabi P. et al The effect of enteric-coated, delayed-release peppermint oil on irritable bowel syndrome.. Digest Diseas Sci 2010; 55: 1385-1390
    Search in Google Scholar
  • 17 Liu JP, Yang M, Liu Y. et al Herbal medicines for treatment of irritable bowel syndrome.. Coch Data Syst Rev 2006; 1: CD004116
    Search in Google Scholar
  • 18 Shi J, Tong Y, Shen JG. et al Effectiveness and safety of herbal medicines in the treatment of irritable bowel syndrome: A systematic review.. World J Gastroenterol 2008; 14 (03) 454
    CrossrefPubMedSearch in Google Scholar
  • 19 Koch E, Brauch S, Treffinger H. et al Beitrag schaumhemmender Effekte von Pfefferminz- und Kümmelöl zu den karminativen Wirkungen von Menthacarin.. Z Phytother 2015; 36 (01) P11
    Search in Google Scholar
  • 20 Myers SR, Hawrelak J, Cattley T.. Essential oils in the treatment of intestinal dysbiosis: A preliminary in vitro study.. Altern Med Rev 2009; 14 (04) 380-384
    PubMedSearch in Google Scholar
  • 21 Lauche R, Janzen A, Lüdtke R. et al Efficacy of caraway oil poultices in treating irritable bowel syndrome – A randomized controlled cross-over trial.. Digestion 2015; 92 (01) 22-31
    CrossrefPubMedSearch in Google Scholar
  • 22 Adam B, Liebregts T, Best J. et al A combination of peppermint oil and caraway oil attenuates the post-inflammatory visceral hyperalgesia in a rat model.. Scand J Gastroenterol 2006; 41 (02) 155-160
    PubMedSearch in Google Scholar
  • 23 Chen C, Tao C, Liu Z. et al A randomized clinical trial of berberine hydrochloride in patients with diarrhea-predominant irritable bowel syndrome.. Phytother Res 2015; 29 (11) 1822-1827
    CrossrefPubMedSearch in Google Scholar
  • 24 Madisch A, Holtmann G, Plein K. et al Treatment of irritable bowel syndrome with herbal preparations: Results of a double-blind, randomized, placebo-controlled, multi-centre trial.. Aliment Pharmacol Ther 2014; 19 (03) 271-279
    Search in Google Scholar
  • 25 Buchert D.. Wirkung einer fixen Kombination bei gesicherter Non-Ulcus-Dyspepsie.. Z Phytother 1994; 15 (01) 24-25
    Search in Google Scholar
  • 26 Holtmann G, Madisch A, Hotz J. et al Treatment of functional dyspepsia with a herbal preparation – Results of a doubleblind, randomized, placebo-controlled, multicenter trial.. Gastroenterology 1999; 116: AG0275
    Search in Google Scholar
  • 27 Rösch W, Vinson B, Sassin I.. A randomised clinical trial comparing the efficacy of a herbal preparation STW 5 with the prokinetic drug cisapride in patients with dysmotility type of functional dyspepsia.. Z Gastroenterol 2002; 40 (06) 401-408
    PubMedSearch in Google Scholar
  • 28 Sallon S, Ben-Arye E, Davidson R. et al A novel treatment for constipation-predominant irritable bowel syndrome using Padma Lax, a Tibetan herbal formula.. Digestion 2002; 65 (03) 161-171
    CrossrefPubMedSearch in Google Scholar
  • 29 Bortolotti M, Porta S.. Effect of red pepper on symptoms of irritable bowel syndrome: Preliminary study.. Digest Diseas Sci 2011; 56: 3288-3295
    Search in Google Scholar
  • 30 Brinkhaus B, Hentschel C, Keudell CV. et al Herbal medicine with curcuma and fumitory in the treatment of irritable bowel syndrome: A randomized, placebo-controlled, double-blind clinical trial.. Scand J Gastroenterol 2005; 40 (08) 936-943
    CrossrefPubMedSearch in Google Scholar
  • 31 Davis K, Philpott S, Kumar D. et al Randomised double-blind placebo-controlled trial of aloe vera for irritable bowel syndrome.. Int J Clin Pract 2006; 60 (09) 1080-1086
    CrossrefPubMedSearch in Google Scholar
  • 32 Lauche R, Kumar S, Hallmann J. et al Efficacy and safety of Ayurvedic herbs in diarrhoea-predominant irritable bowel syndrome: A randomised controlled crossover trial.. Compl Ther Med 2016; 26: 171-177
    Search in Google Scholar
  • 33 van Tilburg MA, Palsson OS, Ringel Y. et al Is ginger effective for the treatment of irritable bowel syndrome? A double blind randomized controlled pilot trial.. Compl Ther Med 2014; 22 (01) 17-20
    Search in Google Scholar
  • 34 Saito YA, Rey E, Almazar-Elder AE. et al A randomized, double-blind, placebo-controlled trial of St John's wort for treating irritable bowel syndrome.. Offic J Am Coll Gastroenterol 2010; 105 (01) 170-177
    Search in Google Scholar
  • 35 Oka T, Okumi H, Nishida S. et al Effects of Kampo on functional gastrointestinal disorders.. Bio Psycho Soc Med 2014; 8: 1-9
    Search in Google Scholar
  • 36 Zhang W, Sun JH, Pei LX. et al Traditional Chinese medicine for treatment of irritable bowel syndrome: An overview of systematic reviews and metaanalyses.. World Chi J Digestol 2014; 22: 1747-1755
    Search in Google Scholar
  • 37 Li Q, Liu F, Hou Z. et al Treatment of constipation-predominant irritable bowel syndrome by focusing on the liver in terms of Traditional Chinese Medicine: A meta-analysis.. J Trad Chin Med 2013; 33 (05) 562-571
    Search in Google Scholar
  • 38 Xiao Y, Liu Y, Huang S. et al The efficacy of Shugan Jianpi Zhixie therapy for diarrhea-predominant irritable bowel syndrome: A meta-analysis of randomized, double-blind, placebo-controlled trials.. PloS One 2015; 10 (04) e0122397
    PubMedSearch in Google Scholar
  • 39 Shi J, Tong Y, Shen JG. et al Effectiveness and safety of herbal medicines in the treatment of irritable bowel syndrome: A systematic review.. World J Gastroenter 2018; 14 (03) 454
    Search in Google Scholar
  • 40 Bian Z, Wu T, Liu L. et al Effectiveness of the Chinese herbal formula TongXieYaoFang for irritable bowel syndrome: A systematic review.. J Altern Compl Med 2006; 12 (04) 401-407
    Search in Google Scholar
  • 41 Ko SJ, Han G, Kim SK. et al Effect of Korean herbal medicine combined with a probiotic mixture on diarrhea-dominant irritable bowel syndrome: A double-blind, randomized, placebo-controlled trial.. Evid Compl Altern Med 2013; 1: 824605
    Search in Google Scholar