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Synthesis
DOI: 10.1055/a-2784-2363
Paper

A Practical Synthesis of 3-Ylidenephthalides by the Rh-catalyzed Tandem Reactions of Benzoic acids and Alkynyl Chlorides

Authors

  • Huan Jin

    1   Anhui Province Key Laboratory of Value-Added Catalytic Conversion and Reaction Engineering, School of Chemistry and Chemical Engineering, Hefei University of Technology, Hefei, China (Ringgold ID: RIN558979)

  • Tingyu Zhang

    1   Anhui Province Key Laboratory of Value-Added Catalytic Conversion and Reaction Engineering, School of Chemistry and Chemical Engineering, Hefei University of Technology, Hefei, China (Ringgold ID: RIN558979)

  • Yingjie Zuo

    1   Anhui Province Key Laboratory of Value-Added Catalytic Conversion and Reaction Engineering, School of Chemistry and Chemical Engineering, Hefei University of Technology, Hefei, China (Ringgold ID: RIN558979)

  • Xu Zhao

    1   Anhui Province Key Laboratory of Value-Added Catalytic Conversion and Reaction Engineering, School of Chemistry and Chemical Engineering, Hefei University of Technology, Hefei, China (Ringgold ID: RIN558979)

  • Fang Li

    1   Anhui Province Key Laboratory of Value-Added Catalytic Conversion and Reaction Engineering, School of Chemistry and Chemical Engineering, Hefei University of Technology, Hefei, China (Ringgold ID: RIN558979)

  • Yunfei Luo 

    1   Anhui Province Key Laboratory of Value-Added Catalytic Conversion and Reaction Engineering, School of Chemistry and Chemical Engineering, Hefei University of Technology, Hefei, China (Ringgold ID: RIN558979)
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A synthesis of 3-ylidenephthalides with high practicality and efficiency, using benzoic acids and alkynyl chlorides as substrate, was realized by the rhodium catalysis. The utilization of alkynyl chlorides enabled this reaction has advantages of broad substrates scope, mild reaction condition, high selectivity and yields.



Publication History

Received: 12 November 2025

Accepted after revision: 08 January 2026

Accepted Manuscript online:
09 January 2026

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