Bicyclo orthoesters and amide acetals were prepared from the
corresponding triols or diethanolamines using α,α-difluoroalkylamines.
The reaction proceeded under milder conditions than conventional
methods. 4-tert-Butyl-1-(4-ethynylphenyl)trioxabicyclo[2.2.2]octane,
a new class of insecticide, was prepared from a triol in three steps
using a difluoroalkylamine.
bicyclo orthoesters - bicyclo amide acetals - α,α-difluoroalkylamines - protecting groups - polymers
