Abstract
A general and environmentally improved protocol for the cyanation
of aryl halides with the nontoxic cyanide source potassium hexacyanoferrate(II) {K4 [Fe(CN)6 ]} using
copper catalysis and a ligand system based on 1-alkyl-1H -imidazoles is presented. The advantages
of this system are a wide substrate range, high selectivity, easy
handling, and inexpensive reagents.
Key words
copper(I) - cyanation - alkylimidazoles - bromoarenes - nitriles
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