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Synthesis 2009(3): 508-510  
DOI: 10.1055/s-0028-1083293
PSP
© Georg Thieme Verlag Stuttgart ˙ New York

Suzuki-Miyaura Cross-Couplings Mediated by trans-PdBr(N-Succ)(PPh3)2: A Convenient Synthetic Method for Diarylmethanes and Aryl(heteroaryl)methanes

Ian J. S. Fairlamb*, Petr Sehnal, Richard J. K. Taylor*
Department of Chemistry, University of York, Heslington, York, YO10 5DD, UK
Fax: +44(1904)432516; e-Mail: ijsf1@york.ac.uk; e-Mail: rjkt1@york.ac.uk;
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Publication History

Received 4 September 2008
Publication Date:
19 December 2008 (online)

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Abstract

Diarylmethanes can be accessed efficiently by Suzuki-Miyaura cross-couplings of arylboronic acids with benzyl halides mediated by trans-PdBr(N-Succ)(PPh3)2. The methodology can be applied to the synthesis of aryl(heteroaryl)methanes.

Key words

catalysis - palladium - pseudohalide - phosphine

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