The First Synthesis of Allyl Isonitriles from Baylis-Hillman Adducts, and Their Application in the Synthesis of Substituted Imidazo[1,2-a]pyridines and Tetraazadibenzoazulenes [¹]

Abstract

The first report of the stereoselective synthesis of substituted allyl isonitriles from primary allylamines generated from Baylis­-Hillman adducts, and their utilization in a robust isonitrile-based multicomponent reaction in the presence of ammonium chloride to afford substituted imidazo[1,2-a]pyridines, is described.

isonitriles - Baylis-Hillman - allylamines - multicomponent reactions - imidazo[1,2-a]pyridines

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