Abstract
The synthesis of a range of novel 5,7-dichloro-6-azaindoles through
the use of a Fischer cyclization with pyridine hydrochloride in N-methylpyrrolidin-2-one is described.
Dichloro-6-azaindoles are versatile compounds that can be selectively
substituted through a palladium-catalyzed cross-coupling reaction
or a high-yielding lithium-chlorine exchange.
Key words
azaindole - pyrrolopyridine - Fischer cyclizations - metalations - palladium
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