Synthesis of Regioisomerically Pure 5-Functionalized 2′,7′-Dichloro­fluoresceins

Abstract

Regioisomerically pure 2′,7′-dichloro-5-nitrofluorescein was isolated on a multigram scale, and used as an intermediate for the generation of three compounds that might be used for labeling biomolecules, namely the corresponding amino, azido, and (4,6-dichloro-1,3,5-triazin-2-ylamino) derivatives.

Key words

fluorescence - chromophores - condensation - heterocycles - regioselectivity

References and Notes

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