A Novel Synthesis of N-But-3-enyl-α- and β-Amino Acids

Abstract

N-But-3-enyl-α- and β-amino acids can be prepared by cleaving 1,3-oxazolidin-5-ones and 1,3-oxazinan-6-ones in the presence of allylsilanes and boron trifluoride etherate at room temperature in good to excellent yields.

1,3-oxazolidin-5-ones - 1,3-oxazinan-6-ones - amino acids - allylations - Lewis acids

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