Hormone and Metabolic Research, Inhaltsverzeichnis Horm Metab Res 1979; 11(2): 107-111DOI: 10.1055/s-0028-1092690 Originals © Georg Thieme Verlag KG Stuttgart · New York The Activities of Perfused Livers of Control and Streptozotocin Diabetic Rats in the Synthesis of Some Plasma Proteins and Peptides A. Guzdek , M. Sarnecka-Keller , A. Dubin Department of Animal Biochemistry, Institute of Molecular Biology, Jagiellonian University, Cracow, Poland Artikel empfehlen Abstract als PDF herunterladen Artikel einzeln kaufen Abstract By measuring the incorporation of I4C-DL-leucine a decreased capacity of isolated perfused streptozotocin diabetic rat liver to synthetize plasma total proteins, albumin and the seromucoid fraction was found as compared with a control. The relative rate of synthesis of the seromucoid proteins calculated as proportional to the rate of synthesis of albumin or the total plasma proteins was approximately twice as great as in control liver. 14C-DL-leucine was also incorporated in perfused liver into the nonprotein but nondialysable sugar-peptide fraction but the synthesis of the glycopeptide components of this fraction was markedly reduced in diabetic rat liver. Key words Streptozotocin Diabetes - Protein Biosynthesis - Perfusion of Liver - Seromucoid - Total Plasma Protein - Albumin - Serum Peptides PDF (186 kb)
