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Horm Metab Res 1978; 10(3): 231-232
DOI: 10.1055/s-0028-1093441
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© Georg Thieme Verlag KG Stuttgart · New York

Pituitary Responsiveness to Thyrotropin Releasing Hormone in Insulin-Dependent Diabetes Mellitus

J. E. Morley , C.  Klein , W. J. Kalk , B. I. Joffe , D.  Saffer , L. A. Distiller , H. C. Seftel
  • Division of Endocrinology and the Carbohydrate-Lipid Research Unit, Departments of Medicine and Nuclear Medicine, University of the Witwatersrand and Baragwanath Hospital, Johannesburg, South Africa
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Publikationsdatum:
23. Dezember 2008 (online)

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Abstract

The pituitary responses to the intravenous administration of 200 mg of Thyrotropin Releasing Hormone were investigated in 14 poorly controlled insulin dependent diabetic males and in nine matched controls. The mean TSH and prolactin responses in the two groups were similar although both tended to be lower in the diabetics. There was a small FSH rise in 11 of the 23 subjects.

Key words

Pituitary - TRH - Insulin Dependent Diabetes Mellitus